Introduction to Nutrition and Metabolism (6^th Ed.)

Introduction to Nutrition and Metabolism equips readers with an understanding of the scientific basis of what we call a healthy diet. Now in its sixth edition, this highly recognized textbook provides clear explanations of how nutrients are metabolized and gives the principles of biochemistry needed for comprehending the science of nutrition.

This full-color textbook explores the need for food and the uses to which food is put in the body, as well as the interactions between health and diet. Outlining the scientific basis behind nutritional requirements and recommendations, this new edition has been extensively revised to reflect current knowledge.

Features:

• Lists key objectives at the beginning, and summary points at the end of each chapter.
• Accompanying online resources include interactive tutorial exercises based on interpretation of clinical and research data.
• Covers topics including: Chemical reactions and catalysis by enzymes; the role of ATP; digestion and absorption of carbohydrates, fats and proteins; issues associated with being overweight; problems of malnutrition; diet and health; and vitamin and mineral requirements and functions.
• Updated sections focus on the interaction of the gut microbiome and epigenetics with our metabolic responses to diet.
• Provides a foundation of scientific knowledge for the interpretation and evaluation of future advances in nutrition and health sciences.

Following its predecessors, this sixth edition is relevant to any student or practitioner interested in how diet influences our health, including in the fields of nutrition, dietetics, medicine and public health.

Contents

Preface .......................................................................................................................................... xvii

Authors .......................................................................................................................................... xix

Additional Resources on the Website: Metabolism Online – The Virtual Tutorial ........................ xxi

Chapter 1 Why Eat? ..................................................................................................................... 1

Chapter 2 Enzymes and Metabolic Pathways ...................................................................... 21

Chapter 3 The Role of ATP in Metabolism .......................................................................... 53

Chapter 4 Digestion and Absorption .................................................................................... 83

Chapter 5 Energy Nutrition: The Metabolism of Carbohydrates and Fats .................. 121

Chapter 6 Diet and Health: Nutrition and Chronic Noncommunicable Diseases …. 1 73

Chapter 7 Overweight and Obesity ..................................................................................... 223

Chapter 8 Protein- Energy Malnutrition: Problems of Undernutrition ......................... 247

Chapter 9 Protein Nutrition and Metabolism ................................................................... 259

Chapter 10 The Integration and Control of Metabolism ................................................... 293

Chapter 11 Micronutrients: The Vitamins and Minerals .................................................. 323

Index ............................................................................................................................................. 421

David A. Bender was educated at North Ealing Primary School and Greenford County

Grammar School in London and then studied biochemistry at the University of Birmingham

in England from 1965 to 1968. He joined the Courtauld Institute of Biochemistry at the

Middlesex Hospital Medical School as a research assistant in 1968, was appointed as a

lecturer in biochemistry in 1970 and received his PhD (on the metabolism of aromatic

amino acids) from the University of London in 1971. The Middlesex Hospital Medical

School merged with University College London (UCL) in 1987, and he became a member

of the Department of Biochemistry and Molecular Biology at UCL. He was appointed as

senior lecturer in biochemistry in 1994 and professor of nutritional biochemistry in 2009.

He retired from UCL in 2011, with the title of Emeritus Professor. From 1994 until retirement,

he was the assistant faculty tutor to the medical students, and from 1998 he was

the subdean (Education) and director of studies for the early years of the medical course

at UCL.

His research interests have been in the fi eld of amino acid and vitamin nutritional

biochemistry, and he was a member of the working group on vitamins that formed part of

the expert committee that produced the 1991 report on Dietary Reference Values for Food

Energy and Nutrients for the United Kingdom, the European Union expert committee that

produced the 1993 report on Nutrient and Energy Intakes for the European Community

and the Food Safety Authority of Ireland working party on Safe Micronutrient Levels.

In addition to research publications, he has also written a number of books, including:

• Nutritional Biochemistry of the Vitamins , 2nd Edition, 2003, Cambridge University Press.

• Amino Acid Metabolism , 3rd Edition, 2012, Wiley- Blackwell.

• Benders’ Dictionary of Nutrition and Foo