Handbook of Diagnostic Endocrinology (3^rd Ed.)

The clinical laboratory plays a critical role in the diagnosis and management of endocrine and related metabolic disorders, which are leading causes of morbidity and mortality in children and adults. The Handbook of Diagnostic Endocrinology, Third Edition, provides a ready reference for the evaluation, diagnosis, and monitoring of such disorders. This revision incorporates translational medicine, connecting what clinicians need to know with those in research providing a clinical context to which they can relate their molecular findings. This book solves the needs of clinicians and researchers by bringing together in one book endocrinology at the molecular and clinical levels. As the intricacies of intracellular signaling have become better understood, states of hormone resistance are now increasingly recognized. The most common endocrinopathy in westernized countries, the metabolic syndrome, results, to a large extent, from insulin resistance. The complexity of the circulating forms of various hormones are acknowledged in this revision.

1. Maximizing the value of laboratory tests
Raffick A.R. Bowen, Roger L. Bertholf and Brett Holmquist
2. Laboratory investigation of disorders of the pituitary gland
Verena Gounden, Charlotte C. Ellberg and Ishwarlal Jialal
3. Thyroid disease and laboratory assessment
Sridevi Devaraj and Emily Garnett
4. Disorders of the adrenal gland
Roger L. Bertholf
5. Endocrine disorders of the reproductive system
Angela M. Ferguson and Mark A. Cervinski
6. Gastroenteropancreatic tumors
Neeraj Ramarishnan, Seong Hyun Ahn and Ishwarlal Jialal
7. Evaluation of hypoglycemia
William E. Winter and Neil S. Harris
8. Evaluation of hyperglycemia
William E. Winter, David L. Pittman, Sridevi Devaraj, Danni Li and Neil S. Harris
9. Lipoproteins
Anna Wolska and Alan T. Remaley
10. Disorders of calcium metabolism
William E. Winter and Neil S. Harris
11. Laboratory evaluation of endocrine hypertension
William E. Winter and Neil S. Harris
12. Malignancy-associated endocrine disorders
Lori J. Sokoll and Daniel W. Chan
13. Laboratory assessment of acquired immunodeficiency syndrome endocrinopathies
Verena Gounden and Manisha Chandalia
14. Laboratory evaluation of short stature in children
William E. Winter
15. Pregnancy and the fetus
K. Aaron Geno, Mark A. Cervinski and Robert D. Nerenz
16. Disorders of sexual development
William E. Winter, Paul Hiers and Dina N. Greene
17. Transgender endocrinology
Dina N. Greene, Tamar Reisman and Zil Goldstein
18. The endocrinology of aging
Daniel T. Holmes and Gregory Kline

Clinical chemists, chemical pathologists, endocrinologists, and senior medical technologists to aid them in the investigation of endocrine and metabolic disorders

Dr. Winter is a professor of pathology, immunology, and laboratory medicine; pediatrics; and molecular genetics and microbiology at the University of Florida in Gainesville. He is principal investigator for the National Institutes of Health-funded Type 1 Diabetes TrialNet Islet Cell Autoantibody Core Laboratory and Islet Autoantibody Standardization Program. Dr. Winter directs the endocrine autoantibody laboratory that at the University of Florida, has given numerous presentations and has published extensively on behalf of the AACC. A multiple-time winner of the AACC outstanding speaker award, Dr. Winter has served on several AACC annual meeting organizing committees. He is a fellow of the College of American Pathologists and the National Academy of Clinical Biochemistry, which he served as a member of the board of directors. He has contributed more than 200 articles, chapters, and abstracts.
Lori J. Sokoll, Ph.D., FAACC is Professor of Pathology in the Johns Hopkins University School of Medicine and has secondary appointments in Oncology and Urology. She is Associate Director of the Clinical Chemistry Division and Director of the Special Chemistry Laboratory in the Johns Hopkins Hospital. Her research interests are focused on the evaluation and clinical applications of cancer biomarkers. She is an Associate Editor of the AACC publication Journal of Applied Laboratory Medicine.Lori J. Sokoll, Ph.D., FAACC is Professor of Pathology in the Johns Hopkins University School of Medicine and has secondary appointments in Oncology and Urology. She is Associate Director of the Clinical Chemistry Division and Director of the Special Chemistry Laboratory in the Johns Hopkins Hospital. Her research interests are focused on the evaluation and clinical applications of cancer biomarkers. She is an Associate Editor of the AACC publication Journal of Applied Laboratory Medicine.
Dr Holmquist is board certified by the American Board of Clinical Chemistry, a fellow of the Ameri