Starving Cancer Cells: Evidence-Based Strategies to Slow Cancer Progression A Selection of Readings for Health Services Providers

Langue : Anglais

Auteurs : Fried Robert, Carlton Richard M., Fried Dennis A.

Couverture de l’ouvrage Starving Cancer Cells: Evidence-Based Strategies to Slow Cancer Progression

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Starving Cancer Cells: Evidence-Based Strategies to Slow Cancer Progression ? A Selection of Readings for Health Services Providers presents an edited and annotated collection of recent medical journal publications and abstracts illustrating new approaches to treatment derived from the metabolic theory of cancer. It intends to shed an early light on a relatively new approach to our understanding of the cancer cell idiosyncratic metabolic dysfunction, and on evidence-based new treatment strategies derived from that understanding.

The book discusses topics such as tumor starvation by L-arginine deprivation; L-canavanine depriving tumors of L-arginine in pancreatic, multiple myeloma and breast cancer; glucose deprivation and intermittent fasting; glutamine uptake in cancer; the relation of oxygen-starved cancer cells with aspartate; and reducing tolerance of tumor cells to nutrition starvation. The content is presented in a contextualized and practical way in order to facilitate the transition from bench to bedside.

This is a valuable resource for practitioners, oncologists and other members of healthcare chain who are interested in learning more about the most recent tumor cell starvation strategies and how they can improve overall treatment outcome.

1. Introduction2. The Metabolic Theory of Cancer and its Clinical Implications3. Tumor Starvation by L-Arginine Deprivation 4. L-Canavanine Deprives Tumors of L-Arginine 5. Glucose Deprivation and Fasting Strategies6. Tumor Starvation by Deprivation of Glutamine and Aspartate

Dr. Robert Fried is Emeritus Professor, Doctoral Faculty, Behavioral Neuroscience, City University of New York (CUNY), New York, NY. Member American Physiology Society (APS) (Cardiovascular and Respiration division). Formerly, Director of the Rehabilitation Research Institute (RRI), International Center for the Disabled (ICD), New York, NY. Diplomate in Behavioral Medicine, International Academy of Behavioral Medicine, Counseling and Psychotherapy (IABMCP). Fellow, New York Academy of Sciences (NYAS). 1953 - 1956, US Army Signal Corps. Korean Military Advisory Group (KMAG), Seoul, Korea. Hon. Discharge, 1956.
Richard M. Carlton, MD is an integrative physician who includes complementary and alternative approaches in the treatment of numerous medical problems, including migraines, inflammatory bowel disease, and diabetes. He had been Principal Staff Physician, Rehabilitation Research Institute (RRI), ICD-International Center for the Disabled, New York, NY.
Dennis A. Fried, PHD, MPH, MBA is Assistant Professor, Department of Epidemiology, Rutgers School of Public Health, Newark, NJ; Health Science Specialist, U.S. Department of Veterans Affairs, War-Related Illness & Injury Study Center, East Orange, NJ.

Provides extensive comments on scientific publications detailing recent findings about tumor cell auxotrophy applied to tumor cell starvation strategies
Helps the reader to find relevant and practical information on cancer cell starvation, otherwise spread through niched specialized journals, in one single place
Comments on the recent findings putting them in context of clinical practice in order to provide the reader with means of translating high level research to the clinics