Organ Repair and Regeneration Preserving Organs in the Regenerative Medicine Era
Coordonnateurs : Orlando Giuseppe, Keshavjee Shaf
Physician, surgeons and PhD’s in the field of organ transplantation and regenerative medicine, as well as anyone interested in organ preservation techniques, as well as anyone interested in organ preservation techniques
Dr. Shaf Keshavjee completed his medical training at the University of Toronto in 1985, and subsequently trained in General Surgery, Cardiac Surgery and Thoracic Surgery at the University of Toronto followed by fellowship training at Harvard University and the University of London for airway surgery and heart-lung transplantation, respectively. He currently leads a team whose studies in transplantation will have a significant impact on treatment outcomes for patients with lung disease at UHN and around the world. Dr. Keshavjee was appointed UHN’s Surgeon-in-Chief in 2010.
An integral part of the Division of Thoracic Surgery at UHN, Dr. Keshavjee has taken on leadership roles in all facets of this specialized area of care: as a skilled surgeon and Director of the Toronto Lung Transplant Program; and as a researcher and Director of the Latner Thoracic Surgery Research Laboratories. To improve lung function after transplantation, Dr. Keshavjee has developed a lung preservation solution to preserve donor lungs en route to transplant. This solution has become the standard technique used by transplantation programs around the world. Dr.Keshavjee has further attracted worldwide attention for his pioneering research to recondition and repair injured human donor lungs using a combination the Toronto XVIVO Lung Perfusion System, making them suitable for transplantation into patients and enhancing the number of donor lungs that are available.
Dr. Keshavjee has served on the
- Covers all aspects of organ preservation, repair and regeneration
- Addresses the repair of organs that experience an Ischemia/Reperfusion (I/R) injury, those that are intended for transplantation, and specific issues related to each organ
- Presented by editors and authors who are physicians, surgeons and researchers in the field of organ transplantation and regenerative medicine
Date de parution : 01-2021
Ouvrage de 304 p.
19x23.3 cm
Thème d’Organ Repair and Regeneration :
Mots-clés :
ß-cell; Acute kidney injury; Allograft; Autoislet; Collagenase; Damage associated molecular patterns; Decellularization; Defatting; Delayed graft function; Diabetes mellitus; Donation after brain death; Donation after circulatory death; Donation after circulatory determined death; Dynamic preservation; Ex situ perfusion; Exsanguinous metabolic support; Extended criteria grafts; Gene modulation; Heart transplantation; Holy grail; Human renal epithelial cells; Immunosuppression; Innate immunity; Insulin; Ischemia; Ischemia reperfusion injury; Ischemia-reperfusion injury; Islet cell; Islet equivalent; Islet allotransplant; Kidney transplant; Liver transplant; Liver transplantation; Machine perfusion; Marginal heart donation; Mesenchymal stem cell; Mitochondriatransfer; Necroptosis; Necrosis; Normothermic; Normothermic machine perfusion; Organ damage; Organ on demand; Organ repair; Organ transplantation; Pancreas transplant; Pyroptosis; Reactive oxygen species; Reconditioning; Regenerative medicine; RNA interference; Simultaneous pancreas and kidney transplant; Small interfering RNA; Steatosis; Suboptimal donor organs; Tissue engineering; Tolerance; Transplantation; Type-1-diabetes; Viability assessment