Transplantation, Bioengineering, and Regeneration of the Endocrine Pancreas Volume 1
Coordonnateurs : Orlando Giuseppe, Piemonti Lorenzo, Ricordi Camillo, Stratta Robert J., Gruessner Rainer W.G.
Transplantation, Bioengineering, and Regeneration of the Endocrine Pancreas, Volume 1, sets a new standard in transplant and regenerative medicine. The book details the-state-of-the-art in modern whole pancreas and islet transplantation, including donor selection, immunosuppression, complications, allograft pathology, and more. As regenerative medicine is changing the premise of solid organ transplantation, this volume catalogs the technologies being developed and the methods being implemented to bioengineer or regenerate the endocrine pancreas in order to more effectively treat diabetes. Edited and authored by unparalleled leaders in the field, this new volume argues for a much needed synergy between organ transplantation and regenerative medicine.
PART A. WHOLE PANCREAS ALLO-TRANSPLANTATION Section I. Introduction Section II. The Donor Section III. The Recipient Section IV. Complications after Pancreas Allo-Transplantation Section V. Natural History Section VI: State of the Art of Pancreas Transplantation
PART B. ISLET ALLO-TRANSPLANTATION Section I. Introduction and Indications Section II. Donor Selection Section III. Islet Isolation Section V. Current Clinical Results Section VI. Monitoring of Allogeneic Islet Grafts Section VII. Immunomodulatory Technologies Applied to Islet Transplantation Section VIII. Cellular Therapies in Preclinical and Clinical Islet Transplantation
Transplant, regenerative medicine and diabetes investigators, basic scientists, biomedical engineers
At the San Raffaele Scientific Institute (Milan, Italy) Lorenzo Piemonti serves as Director of Diabetes Research Institute and Director of Human Islet Transplantation Program. He also serves as Head of the Beta Cell Biology Unit (Diabetes Research Institute), Director of Human Islet Processing Facility, and coordinator of European Consortium for Islet Transplantation that has been providing Human beta Cell Products for research across state barriers in Europe since 2000. He also serves as Professor in Endocrinology at University “Vita Salute San Raffaele of Milan and as Honorary Visiting Professor at Vrije Universiteit of Brussel. His area of expertise is mainly focused on diabetes and pancreatology. In particular he has large experience about diabetes and pancreatic cancer. He had in the past studied the role of innate immunity in islet cell biology (especially in the human model of islet transplantation in type 1 diabetes recipient) and in pancreatic cancer biology (especially the role of chemokines and chemokine receptor system in inducing leukocytes infiltration). More recently, his research interests includes beta cell replacement, immune tolerance induction strategies, dendritic cell biology, stem cells. He currently serves as section Editor of Cell Transplantation-the Regenerative Medicine Journal and of Current Diabetes Reports, as editorial board of Acta Dibetologia, as Councilor of the International Pancreas and Islet Transplantation Association (IPITA) of T
- Provides comprehensive and cutting-edge knowledge of whole pancreas and islet transplantation
- Includes sections that address donor selection, immunosuppression, complications, allograft pathology, and more
- Offers an update on the progress of regenerative medicine research aimed at beta cells replacement in the treatment of diabetes
Date de parution : 11-2019
Ouvrage de 890 p.
21.4x27.6 cm
