Eicosanoids, Softcover reprint of the original 1st ed. 1996 From Biotechnology to Therapeutic Applications NATO Science Series A: Series, Vol. 283

Proceedings of a NATO ASI held in Erice, Italy, April 27-May 1, 1995.

1. Leukotriene A4 Hydrolase: A Key Enzyme in the Biosynthesis of Leukotriene B4.- 2. Lipoxygenases of Mice and Men.- 3. The Physiological and Therapeutic Significance of Separate Pathways for Prostaglandin Synthesis.- 4. Assessment of Pharmacological Inhibition of PGH-Synthases in Man.- 5. Metabolism of Eicosanoids in Mammalian Cells.- 6. New Approach in Immunometric Assays.- 7. Transcellular Biosynthesis of Arachidonic Acid Metabolites: From in Vitro Investigations to in Vivo Reality.- 8. Polymorphonuclear-Endothelial Cell Interactions and the Control of Coronary Vasculature.- 9. PGHS-2 Dependent Formation of 8-Epi PGF2? by Human Monocytes.- 10. Platelet-Activating Factor Regulates Events at the Vascular Wall.- 11. Studies of Isoprostane Biosynthesis in Man.- 12. N-3 Fatty Acids. Antithromboxane Activity. Effects on Redox Status of Blood Cells.- 13. Receptors and Second Messengers for cys-Leukotrienes.- 14. Prostanoid Receptors: Classification, Characterisation and Therapeutic Relevance.- 15. Microvascular Actions and Interactions of Eicosanoids and Histamine in Inflammation.- 16. Leukotriene Antagonists and Synthetase Inhibitors; Clinical Applications in the Treatment of Bronchial Asthma.- 17. PGI2 and Its Analogs: From Pharmacology to Therapeutic Applications.- 18. Leukotriene Synthesis (FLAP) Inhibition: Biochemistry and Pharmacology of Bay X 1005.