Targeting of Drugs 5, 1996 Strategies for Oligonucleotide and Gene Delivery in Therapy NATO Science Series A: Series, Vol. 290

Proceedings of a NATO ASI held in Cape Sounion, Greece, June 24-July 5, 1995

Gene Therapy for Inherited Genetic Disease: Possibilities and Problems.- Gene Delivery and Therapy: The Case for Cystic Fibrosis.- Immune Responses with Direct Gene Transfer: DNA Vaccines and Implications for Gene Therapy.- Oligonucleotides: Molecular Versions for Optimal Use in Vivo.- Retrovirus Vectors in Gene Therapy: Targeting to Specific Cells.- Adenovirus as Vectors for Gene Therapy.- Receptor-Mediated Gene Delivery with Synthetic Virus-like Particles.- Controllable Gene Therapy: Recent Advances in Non-Viral Gene Delivery.- Genetic Chemistry: Towards Non-Enzymatic Ligation, Sequence-Selective Recognition of DNA, and Self-Assembling Systems for Gene Delivery.- Integrin-Mediated Gene Delivery.- Design, Synthesis, and Cellular Delivery of Antibody Targeted, Radiolabelled Oligonucleotide Conjugates for Cancer Therapy.- Poly(L lysine) Mediated Delivery of Nucleic Acids.- Complement Activation by Polylysine-DNA Complexes.- Nanoparticles as Carriers for Antisense Oligonucleotides.- Efficient Incorporation of Plasmid DNA within Liposomes of Varying Structural Characteristics: Liposomal DNA Integrity and Transfection Efficiency.- pH Sensitive Liposomes as Efficient Carriers for Intracellular Delivery of Oligonucleotides.- Liposomal Delivery of p-Ethoxy Antisense Oligodeoxynucleotides in Chronic Myelogenous Leukemia.- Liposome-Mediated Delivery of Genes and Oligonucleotides for the Treatment of Brain Tumors.- Enzyme Assisted Synthesis of Delivery Systems.- Participants’ Photograph.- Contributors.