Cellular Signal Processing (2nd Ed.) An Introduction to the Molecular Mechanisms of Signal Transduction
Auteurs : Marks Friedrich, Klingmüller Ursula, Müller-Decker Karin
Cellular Signal Processing offers a unifying view of cell signaling based on the concept that protein interactions act as sophisticated data processing networks that govern intracellular and extracellular communication. It is intended for use in signal transduction courses for undergraduate and graduate students working in biology, biochemistry, bioinformatics, and pharmacology, as well as medical students. The text is organized by three key topics central to signal transduction: the protein network, its energy supply, and its evolution. It covers all important aspects of cell signaling, ranging from prokaryotic signal transduction to neuronal signaling, and also highlights the clinical aspects of cell signaling in health and disease. This new edition includes expanded coverage of prokaryotes, as well as content on new developments in systems biology, epigenetics, redox signaling, and small, non-coding RNA signaling.
1. The "Brain of the Cell": Data Processing by Protein Networks
2. Supplying the Network with Energy: Basic Biochemistry of Signal Transduction
3. Evolution of Cellular Data Processing
4. Basic Equipment: G-Proteins, Second Messengers, and Protein Kinases
5. Signal Transduction by Receptors with Seven Transmembrane Domains
6. Signal Transduction by Serine/Threonine Kinase-Coupled Receptors
7. Signal Transduction by Tyrosine Kinase- and Protein Phosphatase Coupled Receptors
8. Eukaryotic Gene Transcription: The Ultimate Target of Signal Transduction
9. Signals Controlling mRNA Translation
10. Signal Transduction by Small G-Proteins: The Art of Molecular Targeting
11. Mitogen-activated Protein Kinase and Nuclear Factor κB Modules
12. Regulation of Cell Division
13. Signal Transduction by Proteolysis, and Programmed Cell Death
14. Signal Transduction by Ions
15. Sensory Signal Processing
16. Signaling at Synapses: Neurotransmitters and their Receptors
17. Putting Together the Pieces: The Approach of Systems Biology
Date de parution : 04-2017
21.9x27.6 cm
Disponible chez l'éditeur (délai d'approvisionnement : 14 jours).
Prix indicatif 83,43 €
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Mots-clés :
Map Kinase Module; Tyr Kinase; signaling; Activation Loop Phosphorylation; cellular biology; MAP2 Kinase; protein; Receptor Tyr Kinases; neural network; E3 Ubiquitin Ligase; interaction domain; ATP Hydrolysis; signal processing; CNG Channel; energy; Trp Channel; biochemistry; CNG; redox switch; Thr Specific Protein Kinases; nitrosylation switch; RAF Kinase; enzyme; AGC Kinase; molecular switch; MAPKKK; GTPase; Jak Stat Pathway; G Protein switch; ATP Bind Site; ATPase; RasBD; phosphorylation; Ubiquitin Ligases; acetylation; Transmembrane Helices; gene regulation; Cellular Data Processing; protein degredation; BK Channel; ADP ribosylation; CRAC Channel; ion channel; DNA Bind Domain; proteolysis; Map Kinase Activate Protein Kinase; receptor; SH3 Domain; signaling pathway; model organism; kinase; evolution; cell membrane; sensor dependent signal; bacteria; human; sensor; stress response; transmembrane protein; adrenergic receptor; parasypathetic receptor; arrestin; hedgehog; heptahelical receptor; cytokine; immunology; tyrosine kinase; cell adhesion molecule; transcription; histone; genetics; nucleosome; chromatin; hormone receptor; ligand controlled transcription factor; chapterone; hypoxic stress; RNA interference; exon; mRNA; cytoskeleton; vesicle transport; nuclear transport; mitogen; scaffold protein; cancer; cell division; cyclin; inhibitor; mitogenic signal; retinoblastoma protein; ubiquitin ligase; Mitotic spindle; cell death; secrease-coupled receptor; second messenger; caspase; ction; voltage gated Na+ channel; polarization; hyperpolarization; osmotic pressure; calcium channel; cational channel; taste; mechanical stimulus; touch; sound; pain; photoreceptor; purine receptor; cannabinoid receptor; vanilloid recetor; narcotic; systems biology; network; topology; quantitative biology; Friedrich Marks; Ursula Klingmüller; Karin Müller-Decker
