Nutrients and Epigenetics
Coordonnateurs : Choi Sang-Woon, Friso Simonetta
Explores the Newly Discovered Link Between Nutrition and Epigenetics
Current research suggests that nutrients are more than just food components and that certain nutrients can impact the expression of genes that lead to the development of chronic diseases. With contributions from experts in both fields, Nutrients and Epigenetics examines the epigenetic phenomena and the fascinating implications of diet on this largely uncharted field.
Generously laden with tables and illustrations, many in color, this book addresses how nutrients alter physiologic and pathologic processes in the human body through epigenetic changes without affecting the DNA sequence. It also explains the detailed molecular structures of epigenetic phenomena and closely examines the current knowledge surrounding the biology of aging and embryonic growth regulation.
Assesses the Likelihood of Clinical Applicability
In one single compendium, this resource delineates the nutritional factors that further much-studied aberrant epigenetic patterns, such as DNA methylation, histone modifications, and chromatin remodeling. The book spotlights the influence of nutrition on epigenetic gene regulation, opening the way for counteracting future disease processes associated with epigenetic phenomena?a step that could potentially change the face of disease prevention and development.
Introduction. Methylation on the nucleosome. Mammalian DNA methyltransferases. Chromatin remodeling and histone modifications. Nutrients and DNA methylation. Nutrients, histone modifications, and chromatin remodeling in chronic inflammation. Nutrients, epigenetics, and embryonic development. Nutrition, epigenetics, and aging. Nutrition, epigenetics, and cancer. Conclusions and future perspectives.
Sang-Woon Choi, MD, PhD, Tufts University, Boston, Massachusetts, USA
Simonetta Friso, MD, PhD, University of Verona, Italy
Date de parution : 10-2019
15.6x23.4 cm
Date de parution : 05-2009
Ouvrage de 240 p.
15.6x23.4 cm
Thèmes de Nutrients and Epigenetics :
Mots-clés :
DNA Methylation; Histone Modifications; histone; Epigenetic Marking; modification; DNA Methyltransferase; acetylation; Set Domain; deacetylases; DNA Methyltransferase Activity; methylation; Methyl Deficient Diet; cpg; Epigenetic Phenomena; island; Bioactive Food Components; bioactive; Modify DNA Methylation; food; Genomic DNA Methylation; components; H4 Acetylation; HDAC Inhibitor; RNA Direct DNA Methylation; Affect DNA Methylation; DNA Methylation Status; SNF Complex; ATP Dependent Chromatin Remodel Complex; Alter DNA Methylation; MTHFR 677TT Genotype; Genomic DNA Hypomethylation; Linker DNA; Polycomb Repressive Complexes; Vitamin B12; PcG Complex