Comprehensive Virology, Softcover reprint of the original 1st ed. 1979 Newly Characterized Vertebrate Viruses Comprehensive Virology Series

The time seems ripe for a critical compendium of that segment of the biological universe we call viruses. Virology, as a science, having passed only recently through its descriptive phase of naming and num­ bering, has probably reached that stage at which relatively few new-truly new-viruses will be discovered. Triggered by the intellectual probes and techniques of molecular biology, genetics, bio­ chemical cytology, and high resolution microscopy and spec­ troscopy, the field has experienced a genuine information explosion. Few serious attempts have been made to chronicle these events. This comprehensive series, which will comprise some 6000 pages in a total of about 18 volumes, represents a commitment by a large group of active investigators to analyze, digest, and expostulate on the great mass of data relating to viruses, much of which is now amorphous and disjointed, and scattered throughout a wide literature. In this way, we hope to place the entire field in perspective, and to develop an invalua­ ble reference and sourcebook for researchers and students at all levels. This series is designed as a continuum that can be entered anywhere, but which also provides a logical progression of developing facts and integrated concepts.

1Bunyaviridae.- 1. Introduction.- 2. Structural Components and Their Functions.- 3. Replication of Bunyaviruses.- 4. Genetics.- 5. Defective Interfering Virus.- 6. Conclusions.- 7. References.- 2Arenaviruses.- 1. Introduction.- 2. Historical Considerations.- 3. Pathobiology.- 4. Morphologic and Physical Properties.- 5. Proteins.- 6. Nucleic Acids.- 7. Internal Components of the Virus.- 8. Replication in Cultured Cells.- 9. Interference and Defective Interfering Particles.- 10. Concluding Remarks.- 11. References.- 3Coronaviridae.- 1. Introduction.- 2. Virions.- 3. Growth Properties in Cell and Organ Culture.- 4. Multiplication of Virus.- 5. Alteration in Host Cell Metabolism.- 6. Defective Virus and Viral Interference.- 7. Pathogenesis of Coronavirus Disease.- 8. Persistent Infections.- 9. Genetics.- 10. Conclusion.- 11. References.- 4Caliciviruses.- 1. Introduction and Classification.- 2. Natural History and Disease Aspects.- 3. Antigenic Aspects.- 4. Caliciviruses in Cultured Cells.- 5. The Virion.- 6. Defective Interfering Virus.- 7. Concluding Remarks.- 8. Addendum.- 9. References.- 5Orbiviruses.- 1. Introduction.- 2. Propagation and Assay Systems.- 3. The Virion.- 4. Replication.- 5. Antigenic Properties.- 6. Epizootiology.- 7. Concluding Remarks.- 8. References.- 6Icosahedral Cytoplasmic Deoxyriboviruses.- 1. Introduction.- 2. Classification and General Biological Properties of Icosahedral Cytoplasmic Deoxyriboviruses.- 3. Size, Morphology, and Structure.- 4. Physical Properties.- 5. Chemical Composition.- 6. Replication.- 7. Conclusions and Prospects for the Future.- 8. References.- 7Fish Viruses and Viral Infections.- 1. Introduction.- 2. Fish Herpesviridae.- 3. Fish Iridoviridae.- 4. Fish Reoviridae.- 5. Fish Rhabdoviridae.- 6. Fish Retroviridae.- 7. Unclassified and Putative Fish Viruses Associated with Neoplasia.- 8. Unclassified and Putative Fish Viruses.- 9. References.- 8Viruses of Human Hepatitis A and B.- 1. Introduction: Recognition of Hepatitis Viruses.- 2. Hepatitis B Virus (HBV).- 3. Course of HBV Infection.- 4. Disease Associated with HBV Infection.- 5. Epidemiology of HBV.- 6. Hepatitis A Virus (HAV).- 7. Course of HAV Infection.- 8. Immunity to HAV.- 9. Disease Associated with HAV Infection.- 10. Epidemiology of HAV Infections.- 11. References.