Advances in Nutraceutical Applications in Cancer: Recent Research Trends and Clinical Applications Recent Research Trends and Clinical Applications Nutraceuticals Series

Dietary supplements and nutraceuticals such as Vitamin A and D, Omega-3 and probiotics are used as part of the cancer treatment as complimenting the main therapy. Several Nutraceuticals have shown to boost the immune responses, while emerging clinical studies and other research suggests that some plant-based agents may, indeed, impact late-stage cancer, influencing molecular processes corrupted by tumor cells to evade detection, expand clonally, and invade surrounding tissues.

Advances in Nutraceutical Applications in Cancer: Recent Research Trends and Clinical Applications

is an attempt to collect evidence and related clinical information of application of Nutraceuticals to be used in cancer treatment or compliment the cancer treatment. It contains 16 chapters written by experts in related field?s and covers many different aspects of the formulation and development of Nutraceuticals for cancer applications. This book covers efficacy, safety and toxicological aspects of nutraceuticals. It also addresses various novel drug delivery systems of nutraceuticals with anticancer properties, as well as nutraceuticals as supplements for cancer prevention.

Features:

• Offers a comprehensive view of neutraceuticals? role in cancer prevention and treatment

• Covers the applications and implications of neutraceuticals in prostate, colorectal, breast and gynecological cancers

• Discusses the principles of neutrigenomics and neutrigenetics in cancer prevention

• Explors the role of probiotics and micronutrients in cancer treatment and prevention

Nutraceuticals can alter the gut microbiota. Gut microbiome undergoes changes during the disease status and followed by the cancer treatment. Nutraceutical?s role in proliferation and prevention of gynecological cancers, nutraceutical?s role in proliferation and prevention of prostate cancer and role of micronutrients in cancer prevention, both pros and cons, are some of the topics discussed in various chapters in this book. This book is addressed to scientists, clinicians, and students who are working in the area of Nutraceutical applications in cancer treatment.

Contents

Preface......................................................................................................................vii

Editors .......................................................................................................................ix

Contributors ..............................................................................................................xi

Chapter 1 Role of Micronutrients in Cancer Prevention and

Intervention—Pros and Cons ...............................................................1

Anjelika Chatwal and Yashwant V. Pathak

Chapter 2 Nutraceuticals as Supplements for Cancer Prevention ....................... 19

Nicholas Micciche, Brianna Choyce, and Yashwant V. Pathak

Chapter 3 Nutraceutical’s Role in Proliferation and Prevention

of Prostate Cancer .............................................................................. 39

Raghunandan Yendapally and Donald Sikazwe

Chapter 4 Nutraceutical’s Role in Proliferation and Prevention

of Colorectal Cancer .......................................................................... 61

Mayur M. Patel, Shruti U. Rawal, and Jayvadan K. Patel

Chapter 5 Nutraceuticals’ Role in Proliferation and Prevention

of Breast Cancer ............................................................................... 115

Sadaf Aslam and Beata Casanas

Chapter 6 Nutraceutical’s Role in Proliferation and Prevention

of Gynecological Cancers ................................................................ 133

Aaishwarya B. Deshmukh, Jayvadan K. Patel, and Bharat Mishra

Chapter 7 Mechanism and Role of Probiotics in Suppressing

Bowel Cancer ..............................................................................153

Aaishwarya B. Deshmukh, Jayvadan K. Patel, and Bharat Mishra

Chapter 8 Effect of Nutraceuticals on Gut Microbiota—What Is the

Deal in Cancer? ................................................................................ 171

Andréa Burgess, Asra Sami, and Sheeba Varghese Gupta

Chapter 9 Nutrigenomics and Nutrigenetics in Cancer Prevention .................. 191

Komal Parmar and Jayvadan K. Patel

Chapter 10 Novel Drug Delivery Systems for Nutraceuticals with

Anticancer Properties .......................................................................207

Priyanka Bhatt, Imran Vhora, and Rohan Lalani

Chapter 11 Delivery Strategies and Formulation Approaches of

Anticancer Nutraceuticals ................................................................ 239

Sunita Dahiya and Rajiv Dahiya

Chapter 12 Efficacy, Safety, and Toxicological Aspects of Nutraceuticals ........269

Jayvadan K. Patel and Anita Patel

Chapter 13 Dietary Habits and Susceptibility to Various Cancers ..................... 291

Kimberly Padawer and Yashwant V. Pathak

Chapter 14 Indian Diet and Cancer Prevention ..................................................307

Vasudha Pritipaul, Asra Sami, and Sheeba Varghese Gupta

Chapter 15 Dietary Isoflavones-Mechanism and Efficacy in Cancer

Prevention and Treatment ................................................................. 325

Richa Dayaramani and Jayvadan K. Patel

Index ...................................................................................................................... 341

Sheeba Varghese Gupta, MPharm, PhD, is an associate professor, Department

of Pharmaceutical Sciences, College of Pharmacy, University of South Florida,

Tampa, Florida. She received her PhD at Wayne State University, Michigan, and

earned her MS in Pharmaceutical Chemistry from Bharati Vidhya Peeth Poona

College of Pharmacy, University of Pune, Maharashtra, India. Her research interests

are novel drug delivery systems, improving oral absorption of poorly absorbed

drugs, and patient outcomes. She has authored many peer-reviewed publications,

book chapters and abstracts.

Dr. Yashwant V. Pathak completed his PhD in Pharmaceutical Technology at

Nagpur University, India, and EMBA and MS in Conflict Management at Sullivan

University. He is professor and associate dean for Faculty Affairs at Taneja College

of Pharmacy, University of South Florida. Tampa, Florida. With extensive experience

in academia as well as industry, he has more than 200 research publications,

including research papers; chapters and reviews; 2 patent and 2 patent application;

and 28 edited books published, including 12 books in nanotechnology and 10 in

nutraceuticals and drug delivery systems. He has several books in cultural studies

and conflict management. He has received several national and international awards.

Dr. Pathak was a recipient of Fulbright Senior Scholar award for Indonesia in the

year 2016–2017. Dr. Yashwant V. Pathak is also an adjunct professor at Faculty of

Pharmacy, Airlangga University, Surabaya, Indonesia.