Nuclear Receptors in Development and Disease

Nuclear Receptors in Development and Disease, Volume 125, the latest volume in the Current Topics in Developmental Biology series, covers nuclear receptors in development and disease, and includes contributions from an international board of authors. New chapters in this release cover the Evolution of Nuclear Receptors and Ligand Signaling: Towards a Soft Key?Lock Model?, The Function and Evolution of Nuclear Receptors in Insect Embryonic Development, Nuclear Receptors in Skeletal Homeostasis, Estrogen Hormone Biology, and the Mechanisms of Glucocorticoid Action During Development.

The book's chapters provide a comprehensive set of reviews that cover such topics as nuclear differentiation and remodeling, evolution of receptors, ligand signaling and neural development.

1. Evolution of Nuclear Receptors and Ligand Signaling: Towards a Soft Key–Lock Model? 2. The Function and Evolution of Nuclear Receptors in Insect Embryonic Development 3. Nuclear Receptors in Skeletal Homeostasis 4. Estrogen Hormone Biology 5. Mechanisms of Glucocorticoid Action During Development 6. Progesterone Receptor Signaling in Uterine Myometrial Physiology and Preterm Birth 7. Roles of Retinoic Acid in Germ Cell Differentiation 8. Retinoid-Related Orphan Receptor and Transcriptional Control of Neuronal Differentiation 9. Nuclear Receptor TLX in Development and Diseases 10. COUP-TF Genes, Human Diseases, and the Development of the Central Nervous System in Murine Models 11. Genetic Investigation of Thyroid Hormone Receptor Function in the Developing and Adult Brain 12. Resistance to Thyroid Hormone Due to Heterozygous Mutations in Thyroid Hormone Receptor Alpha 13. TR2 and TR4 Orphan Nuclear Receptors: An Overview 14. The Role of COUP-TFII in Striated Muscle Development and Disease

• Covers the area of nuclear receptors in development and disease
• Includes contributions from an International board of authors
• Provides a comprehensive set of reviews on topics as nuclear differentiation and remodeling, evolution of receptors, ligand signaling and neural developments