Gene Vaccination: Theory and Practice, Softcover reprint of the original 1st ed. 1998 Principles and Practice Series

This book provides a multidisciplinary approach to genetic vaccines. It covers different aspects of basic immunology, molecular biology, infectious diseases, allergy, as well as the regulatory approach to the emerging field of DNA vaccination.

Introduction: Gene Vaccination, Current Concepts and Future Directions.- Plasmid DNA Vaccination: Mechanism of Antigen Presentation.- The Development of a Multivalent DNA Vaccine for Malaria.- DNA Vaccination with Co-Stimulatory Molecules.- Gene Immunization for the Induction of Antigen-Specific, Non MHC-Restricted Responses.- DNA Vaccines With Rapid Intracellular Degradation are More Effective for Inducing CTL.- Genetic Vaccination Against Tuberculosis.- DNA Gene Vaccination for HIV.- DNA-Based Immunization Against Hepatitis B Virus.- Gene Vaccination for Hepatitis C.- Gene Immunization for Allergic Disorders.- Immunization With DNA Vaccines in Early Life: Advantages and Limitations as Compared to Convential Vaccines.- DNA Vaccination by Somatic Transgene Immunization.- DNA Vaccines: Safety and Efficacy Issues.- Genetic Vaccines — A Revolution in Vaccinology?.

Das Spektrum dieses Buches über genetische Impfung geht über mehrere Gebiete wie die Grundlagen der Immunologie, Molekulare Biologie, Infektionskrankheiten, Allergien bis hin zum neuen Gebiet der DNA-Impfung.