Carcinogen-Driven Mouse Models of Oncogenesis Methods in Cell Biology Series

Carcinogen-Driven Mouse Models of Oncogenesis, Volume 163 contains a series of protocols written by world-leading experts in the field. Each manuscript provides a detailed methodological description to drive carcinogen-mediated oncogenesis in mice. Chapters in this new release include Chemical carcinogenesis in mice as a model of human cancer: Pros and cons, MPA/DMBA-driven mammary carcinomas, Dimethylbenz(a)anthracene-Induced Mammary Tumorigenesis in mice, Urethane-induced lung carcinogenesis, Methylcholanthrene-induced fibrosarcomas, BBN-driven bladder carcinomas, Oral squamous cell carcinomas driven by 4NQO, Analyzing skin tumor development in mice by the DMBA/TPA model, and much more.

Other sections cover DSS/AOM-driven colorectal carcinomas, Diethylnitrosamine-induced liver tumorigenesis in mice, Two-stage 3-methylcholanthrene and butylated hydroxytoluene-induced lung carcinogenesis in mice, Lung carcinomas induced by NNK and LPS, Pristane-induced mammary carcinomas, The 4-NQO mouse model: an update on a well-established in vivo model of oral carcinogenesis, and more.

1. Preface - Chemical carcinogenesis in mice as a model of human cancer: Pros and cons Lorenzo Galluzzi 2. MPA/DMBA-driven mammary carcinomas Aitziber Buqué Martinez 3. Dimethylbenz(a)anthracene-Induced Mammary Tumorigenesis in mice Isabelle Plante 4. Urethane-induced lung carcinogenesis Silvano Sozzani 5. Methylcholanthrene-induced fibrosarcomas Awen Gallimore 6. BBN-driven bladder carcinomas Janos Terzic 7. Oral squamous cell carcinomas driven by 4NQO Nancy J. Philp 8. Analysing skin tumor development in mice by the DMBA/TPA model Cord Brakebusch 9. DSS/AOM-driven colorectal carcinomas David C. Montrose 10. Diethylnitrosamine-induced liver tumorigenesis in mice Peter Hasselblatt 11. Two-stage 3-methylcholanthrene and butylated hydroxytoluene-induced lung carcinogenesis in mice Alison K. Bauer 12. Lung carcinomas induced by NNK and LPS Peter Di 13. Pristane-induced mammary carcinomas Bae Hoon Lee 14. The 4-NQO mouse model: an update on a well-established in vivo model of oral carcinogenesis Pierre Saintigny

• Provides protocols provided by renowned experts in the field
• Presents detailed descriptions of protocols, hence allowing appropriate reproduction of the models
• Includes author notes for each protocol, covering useful tips and troubleshooting