Bioprocess Engineering : Basic Concepts 2nd ed.
Langue : Anglais
Auteurs : SHULER Michael, FIKRET Kargi
This concise yet comprehensive text introduces the essential concepts of bioprocessing-internal structure and functions of different types of microorganisms, major metabolic pathways, enzymes, microbial genetics, kinetics and stoichiometry of growth and product information-to traditional chemical engineers. It explores the engineering principles necessary for bioprocess synthesis and design, and illustrates the application of these principles to modern biotechnology for production of pharmaceuticals and biologics, solution of environmental problems, production of commodities, and medical applications.
I. INTRODUCTION
1. What Is a Biochemical Engineer?
II. THE BASICS OF BIOLOGY: AN ENGINEER'S PERSPECTIVE
2. An Overview of Biological Basics
3. Enzymes
4. How Cells Work
5. Major Metabolic Pathways
6. How Cells Grow
7. Stoichiometry of Microbial Growth and Product Formation
8. How Cellular Information Is Altered and Used
III. ENGINEERING PRINCIPLES FOR BIOPROCESSES
9. Operating Considerations for Bioreactors for Suspension and Immobilized Cultures
10. Selection, Scale-up, Operation, and Control of Bioreactors
11. Recovery and Purification of Products
IV. APPLICATIONS TO NONCONVENTIONAL BIOLOGICAL SYSTEMS
12. Bioprocess Considerations in Using Animal Cell Cultures
13. Bioprocess Considerations in Using Plant Cell Cultures
14. Utilizing Genetically Engineered Organisms
15. Medical Applications of Bioprocess Engineering
16. Mixed Cultures
Epilogue
Index
Appendix 1. Glossary of Specialized Terms
Appendix 2. Industrial Bioprocesses.
- NEW- Introduces concepts of validation and Good Manufacturing Practice (GMP).
- NEW- Updated coverage of concepts.
Shows students the connection between traditional ideas and emerging areas-such as tissue engineering and gene therapy. - NEW- Material on functional genomics and cellular engineering.
Provides students with new developments in biology as they impact bioprocess engineering. - NEW- Expanded discussion of modeling approach.
Presents students with a clarified section on models in continuous cultures and adds cybernetic modeling. - NEW- Expanded coverage of chromatography.
Introduces students to discussions of IMAC (immobilized metal affinity chromatography), use of fusion proteins, and porous supports. - NEW- Expanded sections on metabolic e
Date de parution : 10-2001
Ouvrage de 552 p.
18.5x24 cm
Thèmes de Bioprocess Engineering : Basic Concepts 2nd ed. :
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