Autophagy in Health and Disease

Preface - Autophagy: An old mechanism with new challenges ahead Aitziber Buqué and Lorenzo Galluzzi 1. Nucleophagy mediators and mechanisms Margarita-Elena Papandreou and Nektarios Tavernarakis 2. Scaffold proteins in bulk and selective autophagy Christopher Eickhorst, Mariya Licheva and Claudine Kraft 3. A global view of the miRNA-mitophagy connexion Flavie Strappazzon 4. Crosstalk between autophagy and apoptosis: Mechanisms and therapeutic implications Andrew Thorburn 5. Autophagy in immunity Christian Münz 6. Autophagy in cardiovascular health and disease  Mahmoud Abdellatif, Senka Ljubojevic-Holzer, Frank Madeo and Simon Sedej 7. Autophagy in kidney disease: Advances and therapeutic potential Divya Bhatia and Mary E. Choi 8. Autophagy in chronic lung disease Alexandra C. Racanelli, Augustine M.K. Choi and Mary E. Choi 9. Autophagy contribution to motor neuron disease pathology Natalia Rodríguez-Muela 10. Strategies employed by viruses to manipulate autophagy Nilima Dinesh Kumar, Jolanda M. Smit and Fulvio Reggiori 11. Crinophagy mechanisms and its potential role in human health and disease Tamás Csizmadia and Gábor Juhász 12. Autophagy role in environmental pollutants exposure Gemma G. Martínez-García and Guillermo Mariño 13. Genetic defects of autophagy linked to disease Milana Fraiberg and Zvulun Elazar 14. C. elegans to model autophagy-related human disorders Shi Q. Wong, Anita V. Kumar, Joslyn Mills and Louis R. Lapierre 15. Drosophila as a model to understand autophagy deregulation in human disorders Donna Denton, Louise O'Keefe and Sharad Kumar

Equally addressed to expert researchers who may want to extend their technical portfolio, and to beginners in this exciting and rapidly growing field of investigation.

• Provides an outstanding panel of recognized experts in the field who discuss the latest in autophagy
• Includes critical discussions of autophagy in the context of each major human disorder
• Models autophagy-related human pathologies in lower eukaryotes