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Cancer principles & practice of oncology: annual advances in oncology (hardback), Volume 2 Annual Advances in Oncology

Langue : Anglais

Coordonnateurs : DeVita, Jr. Vincent T., Lawrence Theodore S., Rosenberg Steven A.

Couverture de l’ouvrage Cancer principles & practice of oncology: annual advances in oncology (hardback)

Announcing the second volume of DeVita, Lawrence and Rosenberg's groundbreaking series, Cancer: Principles & Practice of Oncology—Annual Advances in Oncology. This series of annual volumes focuses on the most significant changes in oncologic research and practice that have taken place during the preceding year. Each volume identifies scientific and clinical areas in oncology that are rapidly changing and show a high potential for affecting the management of cancer patients in the future. These areas may reflect current controversies in oncology and every effort is made to provide clear direction for the practicing oncologist.

Section Editors iii

Contributing Authors iv

Preface xv

P

TRI

ART 1:PLE-NEGATIVE BREAST CANCER1.

Epidemiology to Treatment.........................1

Triple-Negative Breast Cancer: FromCLIFFOR

D A. HUDIS2.

and Basal Breast Cancers?..........................3

What is the Difference between Triple-NegativeMELANIE

D. SEAL AND STEPHEN K. CHIA3.

10,000 Feet..............................................8

Triple-Negative Breast Cancers: A View fromMAN

DIRA RAY AND BLASE N. POLITE4.

Triple-Negative and Basal-Like Breast

Cancer: Promising Clinical Target or

Only a Marker?......................................14

Epidermal Growth Factor Receptor inMONIKA L. BURNESS, TATYANA A. GRUSHKO, AN

DOLUFUNMILAYO I. OLO

PADE5.

Antiangiogenic Agents ............................. 24

Triple-Negative Breast Cancer: Role ofSALLY GREENBERG AN

D HOPE S. RUGO6.

Tumor Suppression: A Repair-Centric

Perspective.............................................30

BRCA Gene Structure and Function inCONLETH G. MUR

PHY ANDMARY ELLEN MOYNAHAN

7.

Triple-Negative Breast Cancer...................39

Poly (ADP-Ribose) Polymerase Inhibitors inELIZABETH A. COMEN AN

D MARK ROBSON8.

Specific Chemotherapy Agents...................44

Triple-Negative Breast Cancer: Role ofSTEVEN J. ISAKOFF

9.

Androgen Receptor ................................. 53

Triple-Negative Breast Cancer: Role of theAYCA GUCAL

P AND TIFFANY A. TRAINAP

LOCAL THERA

OF LIVER METASTASES

ART 2:PIES IN THE TREATMENT10.

Treatment of Liver Cancer........................57

Introduction to Local Therapies in theWILLIAM

D. ENSMINGER AND ALFRED E. CHANG11.

Hepatic Imaging for Metastatic Disease.......59P

ETER S. LIU AND ISAAC R. FRANCIS12.

Metastasis: Evolving Role in the Setting of

Improving Systemic Therapies and Ablative

Treatments in the 21st Century..................69

Surgical Treatment of Hepatic ColorectalKAORI ITO, ANAN

AN

D GOVINDARAJAN, HIROMICHI ITO,D YUMAN FONG13.

Hepatic Malignancies...............................77

Thermal Ablative Therapies for SecondarySKYE C. MAYO AN

D TIMOTHY M. PAWLIK14.

Liver Cancer...........................................84

Focused Ultrasound as a Local Therapy forKRISZTINA FISCHER, WLA

DYSLAW GEDROYC, ANDFERENC A. JOLESZ

15.

Patients with Resectable Liver Metastases....91

The Role of Chemotherapy in ManagingTHORVAR

MICHAEL L. KEN

DUR R. HALFDANARSON,DRICK, AND AXEL GROTHEY16.

via the Operative and Percutaneous

Techniques for Patients with Isolated and

Unresectable Liver Metastases...................98

Development of Isolated Hepatic PerfusionH. RICHAR

D ALEXANDER, JR., ANDCAROLINE C. BUTLER

17.

Infusion Pumps.....................................108

Implanted Hepatic ArterialMARGARET K. CALLAHAN AN

DNANCY E. KEMENY

18.

Management of Liver Metastases ............. 116

Emerging Role of Radiotherapy in theANAN

D SWAMINATH AND LAURA A. DAWSON19.

Metastatic Liver Cancer..........................122

Chemoembolization for Primary andELENI LIA

PI AND JEAN-FRANCOIS H. GESCHWIND20.

for Primary and Metastatic Hepatic

Malignancies ........................................129

Radioembolization (Yttrium-90 Microspheres)AN

DREW S. KENNEDY AND RIAD SALEMP

CHEMOTHERA

CANCER

ART 3:PY FOR COLORECTAL21.

Colorectal Cancer..................................143

Introduction to Chemotherapy forE

DWARD CHU22.

Biology of Colorectal Cancer...................144MUHAMM

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