Surgical and Medical Treatment of Osteoporosis Principles and Practice

Osteoporosis is the most common bone disease and is associated with pathological fractures that can lead to significant morbidity. It represents an economic burden to the health care system, directly linked to an ageing population. Guidelines on osteoporosis prevention have been published but these do not provide the required specialised knowledge for the treating physician. This book 'fills the gap' and focuses on the principles of surgical and medical treatment of osteoporosis. It aims to improve education and provide answers based on current evidence, helping doctors follow best practice, improve patient care and outcomes, and minimise the complications of medical and surgical management.

Definition, risk factors, and epidemiology of osteoporosis. Pathogenesis: Molecular mechanisms of osteoporosis. Osteoporosis: Biochemical investigations. Diagnosis: Radiological investigations. Development of a fragility liaison service. NICE guidelines for medical treatment of osteoporosis: An update. Role of bisphosphonates and denosumab. The role of anabolic agents. Current and emerging pharmacological agents in the treatment of osteoporosis. Monitoring/surveillance of medical treatment. Systemic complications of osteoporosis medical treatment. Complications of medical treatment: Atypical fractures. Biomechanical considerations for fixation of osteoporotic bone. The fix and treat principle: An update. Principles of management of osteoporotic fractures. Can we accelerate the osteoporotic bone fracture healing response? Management of osteoporotic proximal humeral fractures: An overview. Distal humerus fractures in the elderly: To fix or to replace? Distal radius osteoporotic features: My preferred method of treatment. Management of osteoporotic pelvic fractures. Management of osteoporotic acetabular fractures: Fix or replace? Management of osteoporotic proximal intertrochanteric/subtrochanteric femoral fractures. Osteoporotic distal femoral fractures: When to fix and how. Osteoporotic distal femoral fractures: When to replace and how. Osteoporotic long bone fractures: My preferred method of treatment. Management of osteoporotic extra-articular proximal tibial fractures. Osteoporotic ankle fractures: Principles of treatment. Treatment of distal intra-articular/extra-articular tibial fractures. Osteoporotic os calcis fractures: How I manage them. Current trend in kyphoplasty for osteoporotic vertebral fractures. Osteoporotic thoracolumbar fractures: My preferred method of nonoperative treatment. Augmentation of fracture fixation: An update. Complications of surgical treatment for osteoporotic fractures. Total shoulder replacement and osteoporosis: An Update. Total hip replacement and osteoporosis: Current trends. Total knee replacement and osteoporosis: An overview. Rehabilitation of the osteoporotic patient: Is it different?

Peter V. Giannoudis is Professor at the School of Medicine, University of Leeds and Honorary Consultant at Leeds General Infirmary (LGI).

Thomas A. Einhorn, MD, is Professor of Orthopedic Surgery at New York University.