Principles and Practice of Fetal Medicine

This book is a guide to foetal medicine for practising obstetricians. Its key aim is to help improve prenatal and perinatal management of high risk pregnancies, with an emphasis on monitoring and diagnosis. 

Beginning with an overview of prenatal diagnosis, the following sections cover prenatal counselling, non-invasive prenatal screening, invasive diagnostic techniques, laboratory techniques, antenatal use of foetal therapy, prenatal operative scope, ethical and medicolegal aspects, and the future of prenatal diagnosis. The final section offers FIGO best practice guidelines.

This comprehensive guide is highly illustrated with more than 350 clinical photographs, figures and tables.

Key Points

• Practical guide to foetal medicine for practising obstetricians
• Key aim to help improve prenatal and perinatal management of high risk pregnancies
• Includes FIGO best practice guidelines
• Highly illustrated with more than 350 photographs, figures and tables

Section 1: General Aspects of Prenatal Diagnosis

• Revolution in Prenatal Diagnosis
• Multidisciplinary Approach for Prenatal Screening and Diagnosis
• Goals and Issues in The Delivery of Genetic Services in India
• Prenatal Diagnosis: Challenges and Opportunities Obstetrician Perspective

Section 2: Prenatal Genetic Counseling

• Genetic Counseling
• Premarital and Preconception Counseling
• Genetic Counseling in Prenatally Diagnosed Chromosomal Abnormalities
• Preconceptional Counseling and Management
• Role of Genetics in Reproductive Failure
• Genetics and Counseling of Female Hereditary Breast and Ovarian Cancers

Section 3: Prenatal Screening Non-Invasive

• Global Rainbow Healthcare
• First Trimester Screening
• Maternal Serum Screening for Chromosomal Abnormalities
• Newborn Screening
• Screening and Diagnosis of Inborn Errors of Metabolism
• 11 to 13Weeks Scan: A Window to Fetal Abnormalities
• Fetal Anomaly Scan
• Fetal Growth Restriction
• Color Doppler in Fetal Growth Restriction

Section 4: Diagnostic Techniques Invasive

• General Principles of Prenatal Diagnosis: Invasive Prenatal Diagnosis
• Chorionic Villus Sampling
• Amniocentesis
• Cordocentesis
• Fetoscopy

Section 5: Laboratory Techniques

• Genetic Testing: Indications, Types and Principles
• Preimplantation Genetic Diagnosis:
• Intrauterine Infections Leading to Increased Fetal Morbidity and Mortality

Section 6: Antenatal Use of Fetal Therapy

• Principles of Fetal Therapy and Multifetal Pregnancy Reduction
• Intrauterine Transfusion
• Management of Multifetal Pregnancies
• Twin To Twin Transfusion Syndrome
• Pregnancy and Antiepileptic Drug Treatment

Section 7: Prenatal Operative Scope

• Principles of Fetal Surgery
• Fetal Surgery: Why, When and Where?
• Prenatal Diagnosis and Postnatal Therapy of Surgical Anomalies
• Fetal Autopsy for Better Prenatal Diagnosis: Illustrative Cases

Section 8: Ethical and Medicolegal Aspects

• Ethical And Medicolegal Issues of Prenatal Genetic Diagnosis
• Amended Pre-Conception and Pre-Natal Diagnostic Techniques

Section 9: The Future of Prenatal Diagnosis

• Current Status Of Fetal Genomic Diagnosis in Fetal Medicine, Progress And Challenges
• Array-Based Comparative Genomic Hybridization (Array Cgh): Future in Prenatal Diagnosis
• What is the Future?

Section 10: Guidelines

• FIGO: Good Practice Advice
• FIGO: Best Practice In Maternal Fetal Medicine 2015

Appendix I: Growth Charts

Raju R Sahetya MD DGO DFP FCPS FICOG
Practising Gynaecologist, Pushpa Hospital, Mumbai, Maharashtra, India

Jaideep Malhotra MBBS MD FICOG
Professor, Dubrovnik International University, Dubrovnik, Croatia; Managing Director, ART Rainbow-IVF, Agra, Uttar Pradesh, India

Hema Purandarey MS
Mumbai, Maharashtra, India