Hypopigmentation

There are many disorders of a lack of pigmentation in the skin, with different causations

and effects, of which vitiligo is only the best known; this comprehensive text from international

experts will enable clinicians to diagnose the full range of these conditions and suggest

the most effective management options for their patients.

Contents: Basic concepts of melanocyte biology * Approach to hypopigmentation *

Historical review of vitiligo * Epidemiology and classification of vitiligo * Pathophysiology

of vitiligo * Segmental vitiligo * Childhood versus post-childhood vitiligo * Pharmacological

therapy of vitiligo * Surgical treatment of vitiligo * Phototherapy and lasers in the treatment

of vitiligo * Emerging treatments for vitiligo * Tuberous sclerosis complex * Oculocutaneous

albinism * Hermansky-Pudlak syndrome, Chediak-Chigasi syndrome, and Griscelli

syndrome * Piebaldism * Waardenburg syndrome * Alezzandrini syndrome, Margolis

syndrome, Cross syndrome, and other rare genetic disorders * Mosaic hypopigmentation

* Skin disorders causing post-inflammatory hypopigmentation * Infectious and parasitic

causes of hypopigmentation * Melanoma leukoderma * Halo nevi * Drug-induced hypopigmentation

* Hypopigmentation from chemical and physical agents * Guttate hypomelanosis

and progressive hypomelanosis of the trunk (progressive macular hypomelanosis)

1. Basic concepts of melanocyte biology. 2. Approach to hypopigmentation. 3. Historical review of vitiligo. 4. Epidemiology and classification of vitiligo. 5. Pathophysiology of vitiligo. 6. Segmental vitiligo. 7. Childhood versus post-childhood vitiligo. 8. Pharmacological therapy of vitiligo. 9. Surgical treatment of vitiligo. 10. Phototherapy and lasers in the treatment of vitiligo. 11. Emerging treatments for vitiligo. 12. Tuberous sclerosis complex. 13. Oculocutaneous albinism. 14. Hermansky-Pudlak syndrome, Chediak-Chigasi syndrome, and Griscelli syndrome. 15. Piebaldism. 16. Waardenburg syndrome. 17. Alezzandrini syndrome, Margolis syndrome, Cross syndrome, and other rare genetic disorders. 18. Mosaic hypopigmentation. 19. Skin disorders causing post-inflammatory hypopigmentation. 20. Infectious and parasitic causes of hypopigmentation. 21. Melanoma leukoderma. 22. Halo nevi. 23. Drug-induced hypopigmentation. 24. Hypopigmentation from chemical and physical agents. 25. Guttate hypomelanosis and progressive hypomelanosis of the trunk (progressive macular hypomelanosis).

Electra Nicolaidou, MD, PhD Associate Professor of Dermatology and Venereology, 1st Department of Dermatology and Venereology, National and Kapodistrian University of Athens Medical School, and "Andreas Sygros" Hospital for Skin and Venereal Disease, Athens, Greece

Clio Dessinioti, MD, Msc, PhD Clinical Fellow, 1st Department of Dermatology and Venereology, National and Kapodistrian University of Athens Medical School, and "Andreas Sygros" Hospital for Skin and Venereal Disease, Athens, Greece

Andreas D. Katsambas, MD, PhD Emeritus Professor of Dermatology and Venereology, National and Kapodistrian University of Athens Medical School, and Head, Dermatology Clinic, Hygeia Hospital, Athens, Greece