Genomic Data Sharing Case Studies, Challenges, and Opportunities for Precision Medicine
Clinician investigators, clinicians affiliated with academic medical centers, policymakers and regulators will also gain insights that will allow them to navigate the increasingly complex ethical, social and clinical landscape of genomic data sharing.
1. Introduction Jennifer B. McCormick and Jyotishman Pathak 2. From Public Resources to Improving Health: How genomic data sharing empowers science and medicine Laura Lyman Rodriguez and Elena Marie Ghanaim 3. Biobank case example: Marshfield Clinic Catherine A McCarty and Deanna Cross 4. Multidirectional Genetic and Genomic Data Sharing in the All of Us Research Program Katherine Davison Blizinsky, Subhashini Chandrasekharan, Sonya Jooma, Jessica Reusch and Kimberly Ann Thomson 5. A community approach to standards development: the Global Alliance for Genomics and Health (GA4GH) Angela Page, Melissa Haendel, and Robert R. Freimuth 6. Clinical Genomic Data on FHIR®: Case Studies in the Development and Adoption of the Genomics Reporting Implementation Guide Robert Freimuth, Robert Milius, Mullai Murugan and May Terry 7. Genomics Data Sharing Judit Kumuthini, Lyndon Zass, Melek Chaouch, Faisal M. Fadlelmola, Nicola Mulder, Fouzia Radouani, Verena Ras, Chaimae Samtal, Milaine Sergaine, Dassen Sathan, Anisah Ghoorah, Raphael Sangeda, Liberata Mwita, Upendo Masamu, Samar Kamal Kassim, Zoe Gill, Zahra Mungloo-Dilmohamud, and Gordon Wells 8. Data Standardization in the Omics field Judit Kumuthini, Lyndon Zass, Melek Chaouch, Zoe Gill, Verena Ras, Zahra Mungloo-Dilmohamud, Dassen Sathan, Anisah Ghoorah, Faisal Fadlelmola, Christopher Fields, John Van Horn, Fouzia Radouani, Melissa Konopko, Emile Chimusa, Shakuntala Baichoo 9. Data Sharing: The Public’s Perspective James O'Leary 10. Genetic Data Sharing in the View of the EU General Data Protection Regulation (GDPR) Pieter De Smet (LL.M.) – Mahsa Shabani (PhD) 11. Genomic Data Sharing and Intellectual Property Jorge L Contreras 12. Genomic Data Sharing: Case Studies, Challenges, and Opportunities for Precision Medicine Dimitri Patrinos, Michael Lang and Ma’n H. Zawati
Active researchers, basic and translational scientists, clinicians, postgraduates, and students in the areas of genetics, human genomics, pathology and bioinformatics; medical students, pediatricians; internal medicine physicians and residents; genetic counselors, and genetic counseling students; clinical and laboratory genetics trainees (residents and fellows); law students and legal professionals; students and professional in biomedical ethics, research ethics, public policy, and regulatory practice
Dr. Pathak is the Frances & John L. Loeb Professor of Medical Informatics and the Chief of Division of Health Informatics at Weill Cornell Medicine, Cornell University, New York. Prior to joining Weill Cornell, he was the Professor of Biomedical Informatics at Mayo Clinic in Rochester, Minnesota (2007-2015) where he led two major NIH/HHS funded initiatives—the Electronic Medical Records and Genomics (eMERGE) and Strategic Health IT Research Project (SHARP) projects—which have pion
- Covers both technical and ELSI (ethical, legal, and social implications) perspectives on genomic data sharing
- Includes applied case studies of existing genomic data sharing consortia, including the eMERGE Network, Undiagnosed Disease Network, and the Global Alliance for Genomics and Health (GA4GH), among others
- Features chapter contributions from international leaders in genomic data sharing
Date de parution : 12-2022
Ouvrage de 230 p.
19x23.4 cm
Mots-clés :
Incidental findings; secondary findings; genomics; genomics research; genetics; genetic research; bioinformatics; informatics; variant interpretation; multiplex genetic technologies; whole genome sequencing; WGS; genome sequencing; next generation sequencing; genomic research ethics; research ethics; genetic variants; genomic technologies; ethical challenges; ELSI; precision medicine; personalized medicine; individualized medicine; translational genomics; applied genomics; interdisciplinary research; genomic data governance; genomic data sharing; eMERGE Network; Undiagnosed Disease Network; Vanderbilt Biobank; Marshfield Clinic Biobank; Minnesota Authorization; Rochester Epidemiology Project; HIPAA; NIH Data; GINA; Global Alliance for Genomics and Health (GA4GH)