G-Protein-Coupled Receptor Dimers, Softcover reprint of the original 1st ed. 2017 The Receptors Series, Vol. 33
Coordonnateurs : Herrick-Davis Katharine, Milligan Graeme, Di Giovanni Giuseppe
Part I. Introduction.- 1. From Monomers to Dimers and Beyond: An Exciting Journey in the World of the G protein-coupled Receptor Family.- 2. The use of Spatial Intensity Distribution Analysis to Examine G protein-coupled Receptor Oligomerization.- 3. Advanced Microscopy Techniques for Studying G protein-coupled Receptors.- Part II. Receptors.- 4. Light Sensing G protein-coupled Receptor Rhodopsin Dimer.- 5. Extreme Vetting of Dopamine Receptor Oligomerization.- 6. Serotonin receptors.- 7. Cannabinoid and Opioid Receptor Heteromers.- 8. Di/oligomerization of Glycoprotein Hormone Receptors.- 9. Chemokine Receptor Oligomerization to Tweak Chemotactic Responses.- 10. Secretin Receptor Dimerization. Prototypic of Class B GPCR Behavior.- 11. Receptors and RAMPs.- 12. Obligatory Heterodimerization of GABAB Receptor.- 13. Metabotropic Glutamate Receptors. Part III. Assembly and Trafficking.- 14. The monomer/homodimer Equilibrium of G protein-coupled Receptors: Formation in the Secretory Pathway and Potential Functional Significance.- 15. Probing Self-assembly of G protein-coupled Receptor Oligomers in Membranes using Molecular Dynamics Modeling and Experimental Approaches.- 16. Interaction of Membrane Cholesterol with GPCRs: Implications in Receptor Oligomerization.- Part IV. Physiology and Therapeutic Potential.- 17. Allosterism within GPCR Oligomers: Back to Symmetry.- 18. Understanding the Physiological Significance of GPCR Dimers and Oligomers.- 19. Heteromers form Novel Signaling Complexes.- 20. Heteroreceptor Complexes Implicated in Parkinson’s Disease.
Comprehensive overview of the major GCPR dimers
Contributors are some of the leading experts in this field
Addresses both typical and pathological aspects and explores therapeutic potential
Date de parution : 08-2018
Ouvrage de 501 p.
15.5x23.5 cm
Date de parution : 09-2017
Ouvrage de 501 p.
15.5x23.5 cm