Epigenetics of the Immune System Translational Epigenetics Series
Coordonnateurs : Kabelitz Dieter, Bhat Jaydeep
Epigenetics of the Immune System focuses on different aspects of epigenetics and immunology, providing readers with the fundamental mechanisms relating to epigenetics and the immune system. This book provides in-depth information on immune cells as a toolbox in deciphering systematically regulated mechanisms using "omics" and computational biology approaches. In addition, the book presents the translational importance of epigenetics and the immune system in our understanding of pathophysiology in diseases and its therapeutic applications.
Preface
1. An introduction to immunology and epigenetics Jaydeep Bhat, Dieter Kabelitz
2. Plant epigenetics and the “intelligent priming system to combat biotic stress Hemlata Kotkar, Ashok Giri
3. Understanding immune system development: An epigenetic perspective Ayush Madhok, Anjali deSouza, Sanjeev Galande
4. Epigenetic mechanisms in the regulation of lymphocyte differentiation Nina Schmolka, Bruno Silva-Santos, Anita Q. Gomes
5. Epigenetics mechanisms driving immune memory cell differentiation and function Stephen J. Turner, Jasmine Li, Brendan E. Russ
6. Microbiota in the context of epigenetics of the immune system Katarzyna Placek
7. Sequencing technologies for epigenetics: From basics to applications Rosario Michael Piro
8. Advances in single-cell epigenomics of the immune system Jonas Schulte-Schrepping, Humberto J. Ferreira, Adem Saglam, Emily Hinkley, Joachim L. Schultze
9. Machine learning and deep learning for the advancement of epigenomics Magdalena A. Machnicka, Bartek Wilczynski
10. Systems immunology meets epigenetics Wenhui Li, Ziyi Chen, Aiping Wu, F. Xiao-Feng Qin, Lianjun Zhang
11. Epigenetic deregulation of immune cells in autoimmune and autoinflammatory diseases Javier Rodríguez-Ubreva, Tianlu Li, Esteban Ballestar
12. Epigenetics of allergies: From birth to childhood Avery DeVries, Donata Vercelli
13. Epigenetic regulation of normal hematopoiesis and its dysregulation in hematopoietic malignancies Mark Hartmann, Mariam Hakobyan, Jens Langstein, Maximilian Schonung, Sina Stäble, Aurore Touzart, Justyna A. Wierzbinska, Daniel B. Lipka
14. Impact of epigenetic modifiers on the immune system Sajad Ahmad Bhat, Shalini Kashipathi Sureshbabu, Chinna Susan Philip, Shubhada Chiplunkar
Index
Immunologists, Human Geneticists; Medical Geneticists; Researchers and students working in genetics, genomics, biology, molecular biology, biochemistry, chemistry, pharmaceutical science, oncology, psychiatry, neurology, neuroscience, metabolic disorders, inflammatory and infectious disease, internal medicine, and clinical therapy; advanced undergraduate students, graduate students, postgraduates; pharmaceutical company and biotechnology researchers
Jaydeep Bhat obtained his bachelor and master degrees in Biotechnology from North Maharashtra University, Jalgaon, India. In 2009, he joined the lab Prof. Shubhada Chiplunkar at the ACTREC under the umbrella of the Tata Memorial Center, the largest cancer hospital in Asia. He studied the genomic and functional characterization of human gd T cells in leukemia and breast cancer. To continue his scientific interest in characterizing gd T cells, Jay joined the lab of Prof. Kabelitz at the Institute of immunology in Kiel, Germany in September 2011 as a Ph.D. candida
- Provides an overview of most important immune mechanisms, the current status of epigenetics, and how both of them are brought together
- Presents key principles of immune mechanisms in epigenetics, presenting current findings and key principles
- Features in-depth chapter contributions from a wide range of international researchers and specialists in immunology, translational medicine and epigenetics
- Merges two very large areas, covering the unique interrelatedness of epigenetics and immunology
Date de parution : 06-2020
Ouvrage de 384 p.
19x23.3 cm
Thème d’Epigenetics of the Immune System :
Mots-clés :
Aging; ATACseq; Autoimmunity; Autoinflammation; Bcell development; Bcell differentiation; Bioinformatics; Biomarkers; Biotic stress; Bisulfite sequencing; CD4+ T cell; CD8+ T cell; Cellororigin; Childhood allergic disease; Childhood asthma; ChIPseq; Chromatin; Chromatin accessibility; Classification; Commensals; Computation; Deconvolution; Differentiation; DNA methylation; DNMT; Enhancers; Epigenetic; Epigenetic drugs; Epigenetic modifiers; Epigenetic regulation; Epigenetics; Epigenomics; Gene expression regulation; HAT; HDAC; Hematopoiesis; Histone methylation; Histone methyltransferases; Histone modification; Histone modifications; Immune cell; Immune cell development; Immune cells; Immune system; Immunological memory; Leukemia; lncRNAs; Longdistance regulation; Machine learning; Macrophage; Microbial metabolites; Microbiota; miRNAs; Multiomics; Neural networks; Nextgeneration sequencing; NK cells; Plant immunity; Plant memory; SATB1; scATACseq; Sequencing data analysis; Singlecell; Supervised learning; T cell; T cells; Tcell differentiation; Tcell plasticity; Thirdgeneration sequencing; Transcription factor