Applied Genomics and Public Health Translational and Applied Genomics Series

Applied Genomics and Public Health examines the interdisciplinary and growing area of how evidence-based genomic knowledge can be applied to public health, population health, healthcare and health policies. The book gathers experts from a variety of disciplines, including life sciences, social sciences, and health care to develop a comprehensive overview of the field. In addition, the book delves into subjects such as pharmacogenomics, genethics, big data, data translation and analysis, economic evaluation, genomic awareness and education, sociology, pricing and reimbursement, policy measures and economic evaluation in genomic medicine. This book is essential reading for researchers and students exploring applications of genomics to population and public health. In addition, it is ideal for those in the biomedical sciences, medical sociologists, healthcare professionals, nurses, regulatory bodies and health economists interested in learning more about this growing field.

 Part I 1. Genomic Medicine and Public Health Genomics 2. From Genetic Epidemiology to Exposome and Systems Epidemiology 3. Rare Diseases: Genomics and Public Health 4. Applied Genomics and Public Health Cancer Genomics 5. Genomic basis of psychiatric illnesses and response to psychiatric drug treatment modalities 6. Pharmacogenomics and individualized therapy 7. Microbial genomics in Public Health: A translational risk-response aspect 8. Genome informatics pipelines and genome browsers 9. ?ranslational tools and databases in Genomic Medicine 10. Genetic Testing Part II 11. Assessing the stakeholder landscape and stance point on Genomic and Personalized Medicine 12. Healthcare professionals’ awareness and understanding of genomics 13. Genethics and Public Health Genomics 14. Legal aspects of Genomic and Personalized Medicine 15. Genomics, The Internet of Things, Artificial Intelligence and Society 16. Economic evaluation of Genomic and Personalized Medicine interventions: Implications in Public Health 17. Pricing, budget allocation and reimbursement in Genomic Medicine 18. Genetic counseling 19. Defining genetic testing delivery and promotional strategies for Personalized Medicine 20. Regulatory aspects of Genomic Medicine and Pharmacogenomics 21. Genomic Medicine in emerging economies

Public health researchers and students looking to get a greater understanding of applied genomics. Academics from various disciplines, such as medicine, biomedical sciences, healthcare professionals and nurses, regulatory bodies, health economists will find this book useful.

George P. Patrinos is Professor of Pharmacogenomics and Pharmaceutical Biotechnology in the University of Patras (Greece), Department of Pharmacy, Head of Division of Pharmacology and Biosciences of the same Department and holds adjunct Full Professorships at Erasmus MC, Faculty of Medicine, Rotterdam (the Netherlands) and the United Arab Emirates University, College of Medicine, Department of Genetics and Genomics, Al-Ain (UAE). Also, since March 2018, he is Chair of the Global Genomic Medicine Collaborative (G2MC) and since May 2023 Chairman of the Scientific Advisory Board of the ASPIRE Abu Dhabi Precision Medicine Research Institute. He has ample regulatory experience, as he served for 12.5 years as Full Member and Greece’s National representative in the CHMP Pharmacogenomics Working Party of the European Medicines Agency (EMA) and he is still an active member of the European Medicines Agency participating in expert panels to provide scientific advice where needed. George is currently Director of the Laboratory of Pharmacogenomics and Individualized Therapy, the first officially established academic pharmacogenomics laboratory in Greece. His group has keen interest in research covering disciplines from wet and dry lab and public health genomics projects, all focusing on pharmacogenomics and personalized medicine. In particular, his research interests involve discovery work and clinical implementation of pharmacogenomics, focusing in particular in psychiatry but also cardiology and oncology, genomics of rare disorders and transcriptional regulation of human fetal globin genes. Moreover, George’s group is internationally recognized for its involvement in developing National/Ethnic Genetic databases to document the genetic heterogeneity in different populations worldwide and of genome informatics tools to translate genomic information into a clinically meaningful format. Also, George’s group has a k

• Explores the growing application of genomics to population and public health
• Features internationally renowned contributors from a variety of related fields
• Contains chapters on important topics such as genomic data sharing, genethics and public health genomics, genomics and sociology, and regulatory aspects of genomic medicine and pharmacogenomics