The Opiate Receptors (2^nd Ed., 2nd ed. 2011) The Receptors Series, Vol. 23

This new edition covers the latest knowledge on opiate receptors and related receptor subtypes. It discusses many topics pertaining to the unique integrated approach of correlating the biochemical, physiological and pharmacological aspects of opiate reaction.

You’ve Come a Long Way Baby.- The evolution of concepts of opioid receptors.- Pharmacology of opioid drugs.- Opioid receptors: the early years.- Endogenous opioids.- Molecular biology of mu opioid receptors.- Delta Opioid Receptors.- Kappa opioid receptor gene and the regulatory mechanisms of its protein expression.- Opioid receptor signal transduction mechanisms.- Mu opioid receptor mediated analgesia and reward.- Kappa opioid receptor function.- Delta opioid receptor function.- Genetics of opioid receptor functions in mice.- Opioid receptor trafficking.- Opioid receptor dimerization.- Molecular modulation of in vivo tolerance.- Genetics of opioid actions.

In 1988, Gavril W. Pasternak published the first edition of The Opiate Receptors. Dr. Pasternak is affiliated with the Molecular Pharmacology & Chemistry department at the Sloan-Kettering Institute (Memorial Sloan-Kettering Cancer Center).

1. Fully revised and expanded, The Opiate Receptors, 2nd edition presents all the advances made in the field in the past twenty years Covers a wide variety of topics relating to opioid drugs and mu receptors, delta receptors, and kappa opioid receptors 3. Written by leading international researchers in the field, this new edition is as groundbreaking and vital as its predecessor Includes supplementary material: sn.pub/extras