Targeting of Drugs 6, 1998 Strategies for Stealth Therapeutic Systems NATO Science Series A: Series, Vol. 300

Proceedings of a NATO ASI held in Cape Sounion Beach, Greece, June 24-July 5, 1997

Interactions between Blood Components and Artificial Surfaces.- The Mononuclear Phagocyte System: Features Relevant to Interactions with Liposomes.- Stealth™ Therapeutic Systems: Rationale and Strategies.- Long Circulating Liposomes: Evolution of the Concept.- Sterically Stabilized Immunoliposomes: Formulations for Delivery of Drugs and Genes to Tumor Cells in Vivo..- Pegylation of Liposomes in Cell-Specific Targeting: It Does Not Always Make Sense.- Stealth™ Liposomes for the Targeting of Drugs in Cancer Therapy.- Stealth™ Liposomes as Carriers of Doxorubicin.- Liposome-Mediated Delivery of Retinoids.- Applications of Liposome Technology to Overcome Multidrug Resistance in Solid Tumors.- Use of Radiolabeled Liposomes for PEG-Liposome-Based Drug Targeting and Diagnostic Imaging Applications.- Diagnostic and Therapeutic Targeting of Infectious and Inflammatory Diseases Using Sterically Stabilized Liposomes.- Biologically Active Ligand-Bearing Polymer-Grafted Liposomes.- Engineering Stealth™ Liposome Surfaces: Exercises in Colloid Chemistry Principles.- The Role of Hydration in Stabilization of Liposomes: Resistance to Oxidative Damage of PEG-Grafted Liposomes.- Physicochemical Characterization of DOTAP-Containing Lipoplexes by Fluorescent Probes: Relevance to Lipofection.- Steric Stabilization of Cationic Liposome-DNA Complexes: Influence on Morphology and Transfection Activity.- Polysialic Acids: Potential for Long Circulating Drug, Protein, Liposome and Other Microparticle Constructs.- Tailor-Made Soluble Polymer Carriers.- Development of Novel Technologies for the Synthesis of Biodegradable Pegylated Nanoparticles.- Development of a New Class of Nanoparticles which Avoid Phagocytosis by Inhibiting Complement Activation.- Coating of Nanoparticles withSurfactants: Targeting versus Prolonged Circulation.- Recent Developments and Limitations of Poloxamine-Coated Long-Circulating Particles in Experimental Drug Delivery.- PEG-Coated Nanospheres: Surface Optimization and Therapeutic Applications.- Participants’ Photograph.- Contributors.