Nitric Oxide and Free Radicals in Peripheral Neurotransmission, 2000 Nitric Oxide in Biology and Medicine Series, Vol. 2

"Nitric Oxide and Free Radicals in Peripheral Neurotransmission" is a welcome addition to the literature and describes current research into the role of nitric oxide in the peripheral nervous system and its associated organs. Topics covered range from general consideration of nitrergic transmission, in its broadest sense, to elaboration of our current understanding of the role of nitric oxide in transmission in individual peripheral organs, including its role as a backup, or alternate as well as chief transmitter. The influence of nitric oxide and related compounds on the more conventional modes of autonomic transmission are also considered. Aimed at students and researchers in the areas of neuroscience and physiology, "Nitric Oxide and Free Radicals in Peripheral Neurotransmission" also covers the emerging role of abnormal nitric oxide function in disease states and, where appropriate, as potential avenues of therapy.

1. On the Origin and Early Evolution of Neuronal Nitric Oxide Signaling: A Comparative Analysis.- 2. The Nitrergic Transmitter of the Anococcygeus: Lessons and Insights.- 3. Interactions Between Nitric Oxide and Other NANC Inhibitory Neurotransmitters in the Periphery: Clues from the Endothelium.- 4. Nitrergic Neurotransmission in the Lower Urinary Tract and Penile Erectile Tissues.- 5. Nitrergic Neurotransmission in the Enteric Nervous System.- 6. Nitric Oxide and Peripheral Neurotransmission in the Lung.- 7. Nitrergic Neurogenic Control of Resistance Blood Vessels.- 8. Is There Neural Control of Peripheral Resistance Arteries by Nitrergic Nerves?.- 9. Nitric Oxide, Perivascular Neural Transmission, and Migraine.- 10. Presynaptic Modulation of Peripheral Nitrergic Neurotransmission.- 11. Neural Nitric Oxide Synthase and Neutrophil Function.- 12. Nitric Oxide Toxicity in Neuronal Injury and Degeneration.- 13. Peroxynitrite and Nitrergic Neural Transmission: Pathophysiological Implications.- 14. Nitric Oxide, Peripheral Neuropathy, and Diabetes.- 15. Potential Clinical Impact of Nitric Oxide and Nitric Oxide Inhibitors in the Periphery.