Glycans in Diseases and Therapeutics, 2011 Biology of Extracellular Matrix Series
Coordonnateur : Pavão Mauro S.G.
Initially believed to be inactive molecules, glycans are now considered essential for life, both under normal and pathological conditions.
This volume of the series ?Biology of Extracellular Matrix? reviews the most recent findings on the role of glycans in the development of diseases and the possible therapeutic use of this class of molecules. It shows how the interaction of glycans with growth factors, growth factor binding proteins, extracellular proteases, protease inhibitors, chemokines, morphogens, and adhesive proteins regulates inflammation, infection, cancer, atherosclerosis, thrombosis and embryonic stem cell biology. Furthermore, an extensive survey about the structure and pharmacological effects of unique marine glycosaminoglycans is discussed as well as the possibility of using these glycans as therapeutic agents.
Heparan Sulfate Proteoglycan in Inflammation and Angiogenesis.- Heparan Sulfate Proteoglycans in Infection.- Glycans in cancer.- Glycosaminoglycans in atherosclerosis and thrombosis.- Glycans in Embryonic Stem Cells.- Heparan sulfate proteoglycans in cancer progression and therapy.- Structure and biological activities of glycosaminoglycan analogs from marine invertebrates: new therapeutic agents?.
Date de parution : 05-2013
Ouvrage de 188 p.
15.5x23.5 cm
Date de parution : 04-2011
Ouvrage de 188 p.
15.5x23.5 cm
Thèmes de Glycans in Diseases and Therapeutics :
Mots-clés :
Angiogenesis; Cancer; Inflammation; Marine invertebrates; Proteoglycans; Thrombosis