Evidence-Based Neonatal Infections Evidence-Based Medicine Series

Evidence-Based Neonatal Infections is expertly written by David Isaacs, an experienced author renowned for his knowledge in both pediatric infections and evidence-based medicine. It critically analyses the evidence for decision making in neonatal infections.

Evidence-Based Neonatal Infections

* The first evidence-based text on neonatal infections

* Provides practical guidance where evidence is poor

* Complements David Isaacs? Evidence-Based Pediatric Infectious Diseases (9781405148580)

Practical and evidence-based, Evidence-Based Neonatal Infections is designed to help the clinician with day-to-day decisions on the care of newborn babies with possible, probable or proven infections. It considers clinical questions relevant to neonatologists, analysing the evidence carefully and providing recommendations for optimum management of neonatal infectious diseases, whilst reflecting on:

• Efficacy and safety
• Antibiotic resistance
• Cost effectiveness
• Adverse effects
• Ethical considerations

Evidence-Based Neonatal Infections provides a unique reference for neonatologists, pediatricians, trainees, specialist nurses; general practitioners, microbiologists, infection control doctors, and all staff in neonatal units.

About the Author, vi

Preface, vii

1 How to search for evidence, 1

2 Epidemiology, 5

3 Clinical manifestations, 16

4 Laboratory tests, 21

5 Rational antibiotic use, 33

6 Adjunctive treatment, 48

7 Bacterial meningitis, 57

8 Respiratory tract infections, 70

9 Osteomyelitis and septic arthritis, 78

10 Urinary tract infections, 86

11 Necrotizing enterocolitis and gastrointestinal infections, 94

12 Eye Infections, 108

13 Skin and soft tissue Infections, 117

14 Bacterial infections, 128

15 Mycoplasmas, 153

16 Fungal infections, 159

17 Viral infections, 175

18 Other congenital infections, 199

19 Breast milk, 214

20 Surveillance, 223

21 Infection control, 229

22 Developing countries, 244

23 Prevention of neonatal infections, 250

24 Neonatal antimicrobials, 269

Index, 291

David Isaacs is a pediatrician based at The Children's Hospital at Westmead, Sydney and is Clinical Professor of Pediatric Infectious Diseases at the University of Sydney. He has published 12 books, over 300 peer-reviewed publications on neonatal infections, pediatric infectious diseases, immunizations, bioethics and 30 humorous articles. His research interests are neonatal infections, respiratory virus infections, immunizations and ethics. Professor Isaacs is on multiple national and international committees on infectious diseases and immunizations and is a reviewer for the Cochrane Collaboration.