Endocrinology in Clinical Practice (2^nd Ed.)

Endocrinology is a complex specialty that spans a wide range of diseases, disorders, and conditions. The field is now moving toward an increasingly personalized approach to patient management, with a greater focus on mechanisms of disease and biomarkers. Written by internationally renowned specialists, the second edition of Endocrinology in Clinical Practice provides a cutting-edge, problem-orientated approach to the management of clinical problems in endocrinology.

Highlights of the new edition include:

• An overview of neuroendocrine disease
• Strides made by the identification of aryl hydrocarbon receptor?interacting protein mutations in patients with familial isolated pituitary adenomas
• The diverse roles of IGF-I
• Changes in diagnostic imaging and the increasing use of positron emission tomography
• The rapidly increasing incidence of neuroendocrine tumors and their management
• Hereditary primary hyperparathyroidism and multiple endocrine neoplasia
• Mechanistic and genomic advances related to disorders of calcium regulation and infertility
• The endocrinology of aging
• Protocols for pituitary function testing

With complete updates to existing chapters, the second edition also presents new research data, diagnostic techniques, treatment options, and safety concerns related to existing therapies. This edition offers current guidance and scientifically focused information relevant to a range of clinical problems, making it an essential reference for practicing endocrinologists and specialist clinicians.

Familial Isolated Pituitary Adenomas. Neuroendocrine Disease. Pituitary Hormone Replacement Therapy. Surgical Radiotherapeutic Management of Pituitary Disease. Pituitary Radiotherapy. IGF-1 as a Metabolic Hormone. Multiple Endocrine Neoplasia. Gastro-Entero-Pancreatic Neuroendocrine Tumours. Coincidental Adrenal Masses And Adrenal Cancer. Autoimmune Endocrine Disease. Multinodular Goitre, Toxic Adenoma, Thyroiditis. Thyroid Cancer. Non Autoimmune Thyroid Disease. The Genetics Of Hypogonadal Disorders. Amenorrhorea, Hirsutissm And Virilisation. Hypogonadism, Erectile Dysfunction. Endocrine Disorders of Pregnancy. Disorders of Calcium Regulation. Osteoporosis, Osteomalacia And Metabolic Bone Disease. Disorders of Fluid And Electrolyte Balance. Endocrine Hypertension. Obesity. Endocrinology of Aging. Endocrine Emergencies.

Philip E. Harris trained in endocrinology as an MRC Training Fellow at the University of Wales College of Medicine; at St. Bartholomew’s Hospital, London; and The University of Newcastle upon Tyne. In 1990–1991, Dr. Harris worked as an MRC Travelling Fellow at the Endocrine and Reproductive Endocrine units, Massachusetts General Hospital, Boston, USA. In 1994, he was appointed senior lecturer and consultant endocrinologist at King’s College Hospital, London. His main clinical and research interest is in the field of endocrine oncology—in particular, pituitary disease. Dr. Harris is currently vice president for Scientific Affairs, Ipsen Biopharm Ltd. He is also an honorary consultant in endocrinology at University Hospital Lewisham, London.

Pierre-Marc G. Bouloux is the Director of the Centre for Neuroendocrinology at the Royal Free and University College Medical School. He was an MRC Training Fellow under Michael Besser at St. Bartholomew’s Hospital and was subsequently lecturer in medicine at the University Department of Medicine at St. Bartholomew’s Hospital. He has held his present post since 1991. In addition to running a clinical service, he also has a special interest in neuroendocrinology. He has published more than 150 peer-reviewed publications.