Biosynthesis, 2000 Aromatic Polyketides, Isoprenoids, Alkaloids Topics in Current Chemistry Series, Vol. 209
Langue : Anglais
Coordonnateurs : Leeper Finian J., Vederas John C.
This book is the second of two volumes that deal with discovery of chemical pathways of biosynthesis of natural products (secondary metabolites). The first volume covered the use of isotopes in biosynthetic research and the formation of enzyme cofactors and reduced polyketides. This second volume describes biosynthesis of aromatic (unreduced) polyketides, enzymes responsible for cyclization of terpenoids (isoprenoids), and biochemical generation of selected classes of alkaloids (prenylated tryptophan, tropane, pyrrolizidine). Knowledge of the pathways and the techniques to elucidate them opens the door to combinatorial biosynthesis as well as to the production of targeted pharmaceutical agents utilizing a combination of chemistry, molecular biology and protein biochemistry.
Biosynthesis of Aromatic Polyketides.- Cyclization Enzymes in the Biosynthesis of Monoterpenes, Sesquiterpenes, and Diterpenes.- Biosynthesis of Prenylated Alkaloids Derived from Tryptophan.- Tropane and Related Alkaloids.- Biosynthesis and Metabolism of Pyrrolizidine Alkaloids in Plants and Specialized Insect Herbivores.
This series presents critical reviews of the present position and future trends in modern chemical research Short and concise reports on chemistry, each written by the world's renowned experts Still valid and useful after 5 or 10 years
Date de parution : 12-2010
Ouvrage de 247 p.
15.5x23.5 cm
Date de parution : 03-2000
Ouvrage de 247 p.
15.5x23.5 cm
Thèmes de Biosynthesis :
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