Biological Basis of Sex Differences in Psychopharmacology, 2011 Current Topics in Behavioral Neurosciences Series, Vol. 8

Sex matters! Are there differences between the sexes when it comes to brain function and the behaviours that result? This volume attempts to answer this fundamental question. If the answer is ?yes? then this should impact upon our approach to treating mental illness in humans, and to modelling it in animals, as we look for aetiological and pharmacological solutions.

Preface.- Female rats are smarter than males: influence of test, oestrogen receptor subtypes and glutamate.- Differences in sexual behaviour in male and female rodents: role of serotonin.- Sex differences in the cholinergic system in rats: behavioural consequences.- Sex differences in response to stress and expression of depressive-like behaviours in the rat.- Females are more vulnerable to drug relapse, evidence from preclinical studies and role of ovarian hormones and estrogen receptors.- Genetics and sex differences: role of COMT.- Sex differences precipitating anorexia nervosa in females: A novel framework for targeting sex specific neurocircuits and behavior.- Gender differences in developmental disorders - biological causes and treatments.- The estrogen hypothesis of schizophrenia.- Sex and its impact on antidepressants.- Bipolar recurrences after childbirth and possible biological mechanisms.- Introduction to the interaction between gonadal steroids and the central nervous system.- Sex Differences and Hormonal Influences in Human Sensorimotor Gating: Implications for Schizophrenia.

 

 

This volume brings together experts in this field, both psychiatrists and health care professionals with preclinical researchers to review the latest work in this area It gives a thorough overview of how males and females are different in terms of brain function and behaviour The first volume which covers in some depth many illnesses in which sex differences and gonadal steroids are important in terms of aetiology, symptomatology, progression and treatment Includes supplementary material: sn.pub/extras