A Comprehensive Physically Based Approach to Modeling in Bioengineering and Life Sciences
Auteurs : Sacco Riccardo, Guidoboni Giovanna, Mauri Aurelio Giancarlo
A Comprehensive Physically Based Approach to Modeling in Bioengineering and Life Sciences provides a systematic methodology to the formulation of problems in biomedical engineering and the life sciences through the adoption of mathematical models based on physical principles, such as the conservation of mass, electric charge, momentum, and energy. It then teaches how to translate the mathematical formulation into a numerical algorithm that is implementable on a computer. The book employs computational models as synthesized tools for the investigation, quantification, verification, and comparison of different conjectures or scenarios of the behavior of a given compartment of the human body under physiological and pathological conditions.
Part I. Mathematical, Computational, and Physical Foundations1. Elements of Mathematical Modeling2. Elements of Mathematical Methods3. Elements of computational methods4. Elements of Physics
Part II. Balance Laws5. The Rational Continuum Mechanics Approach to Matter in Motion6. Balance laws in integral form7. Balance laws in local form8. Continuum Approach for Multicomponent Mixtures
Part III. Constitutive Relations9. Preliminary Considerations on Constitutive Modeling10. Constitutive Relations for Fluids11. Constitutive Relations for Solids12. Constitutive Relations for Multicomponent Mixtures13. Constitutive Relations in Electromagnetism and Ion Electrodynamics
Part IV. Model Reduction of System Complexity14. Reduction of the Maxwell Partial Differential System15. Electric Analogy to Fluid Flow
Part V. Mathematical Models of Basic Biological Units and Complex Systems16. Cellular Components and Functions: A Brief Overview17. Mathematical Modeling of Cellular Electric Activity18. Mathematical Modeling of Electric Propagation Along Nerve Fibers19. Differential Models in Cellular Functions
Part VI. Advanced Mathematical and Computational Methods20. Functional Spaces and Functional Inequalities21. Functional Iterations for Nonlinear Coupled Systems of Partial Differential Equations22. Time Semidiscretization and Weak Formulations for Initial Value/Boundary Value Problems of Advection–Diffusion–Reaction Type23. Finite Element Approximations of Boundary Value Problems of Advection–Diffusion–Reaction Type24. Finite Element Approximations of Initial Value/Boundary Value Problems of Advection–Diffusion–Reaction Type25. Finite Element Approximation of a Unified Model for Linear Elastic Materials
Part VII. Simulation Examples and Clinical Applications26. Ion Dynamics in Cellular Membranes27. Interaction Between Hemodynamics and Biomechanics in Ocular Perfusion
Part VIII. Examples, Exercises, and Projects28. Coding of Examples Using Matlab Scripts29. Matlab Functions for Algorithm Implementation30. Homework: Exercises and Projects
Appendix A. Elements of Differential Geometry and Balance Laws in Curvilinear Coordinates
Giovanna Guidoboni, PhD, is an applied mathematician with expertise in mathematical and computational modeling of complex fluid flows arising in engineering and biomedical applications. Dr. Guidoboni has promoted the development of interdisciplinary approaches in physiology and ophthalmology at the international level. She co-founded a new peer-reviewed scientific journal titled “Journal for Modeling in Ophthalmology, for which she currently serves as co-Chief Editor and Managing Editor, and a new series of interdisciplinary congresses and doctoral courses creating a forum where ophthalmologists, physiologists, mathematicians, engineers, physicists, and biologists can discuss new ideas on how to address outstanding challenges in ophthalmology.
Aurelio Giancarlo Mauri, MSc, is a Senior Member of the Technical Staff of Micron Technology, where he currently works in the numerical simulation group appointed for the physical modeling of electronic devices. He is the main author of FEMOS-MP (Finite Element Method Oriented Simulator for Multiphysics Problems), a C++ platform for the simulation of
- Presents theoretical (modeling), biological (experimental), and computational (simulation) perspectives
- Features examples, exercises, and MATLAB codes for further reader involvement
- Covers basic and advanced functional and computational techniques throughout the book
Date de parution : 07-2019
Ouvrage de 854 p.
19x23.3 cm