The Zebrafish in Biomedical Research Biology, Husbandry, Diseases, and Research Applications American College of Laboratory Animal Medicine Series
Coordonnateurs : Cartner Samuel, Eisen Judith S., Farmer Susan F., Guillemin Karen J., Kent Michael L., Sanders George E.
The Zebrafish in Biomedical Research: Biology, Husbandry, Diseases, and Research Applications is a comprehensive work that fulfills a critical need for a thorough compilation of information on this species. The text provides significant updates for working vivarium professionals maintaining zebrafish colonies, veterinarians responsible for their care and well-being, zoologists and ethologists studying the species, and investigators using the species to gain critical insights into human physiology and disease. As the zebrafish has become an important model organism for the study of vertebrate development and disease, organ function, behavior, toxicology, cancer, and drug discovery, this book presents an important resource for future research.
I. Introduction
1. History of Zebrafish Research
2. Taxonomy/Phylogeny
3. Zebrafish Genetics
4. Geographic Range and Natural Distribution
5. Behavior of Wild Populations
II. Biology
Appearance, Development, Anatomy, Physiology
6. Zebrafish in Biomedical Research: Head and Body: Anatomy
7. Establishing the Body Plan: The First 24 Hours of Zebrafish Development
Organ Systems: Development, Anatomy, Physiology
8. Zebrafish Integumentary System
9. Zebrafish Pigmentation
10. Respiratory System
11. Skeletal System Morphophysiology
12. Zebrafish Myology
13. It Takes Guts: Development of the Embryonic and Juvenile Zebrafish Digestive System
14. The Zebrafish Cardiovascular System
15. Development of the Zebrafish Pronephric and Mesonephric Kidneys
16. Reproductive System
17. Endocrine Systems
18. Nervous Systems
19. Immunology
20. Physiology: Hematology and Clinical Chemistry, Gas Exchange, and Regulatory Osmolality
Tissues and Organs Associated with Special Senses
21. Zebrafish in Biomedical Research: The Retina and Vision
22. The Mechanosensory Lateral Line System
23. Inner Ear and Hearing
Husbandry
24. Introduction to Zebrafish Husbandry
25. Aquatic Facility Design Considerations: Incorporating Aquatics into an Animal Facility
26. Aquatic Housing
27. Cleaning and Disinfection of Life Systems
28. Zebrafish Aquatic Systems: Preventative Maintenance and Troubleshooting
29. Water Quality for Zebrafish Cultura
30. Recirculating Aquaculture Systems (RAS) for Zebrafish Culture
31. Zebrafish Breeding and Colony Management
32. Zebrafish Larviculture
33. Zebrafish Nutrition--Moving Forward
34. Anesthesia, Analgesia, and Euthanasia of the Laboratory Zebrafish
35. Health Xurveillance Programs
36. Importation and Quarantine
37. Export and Transportation of Zebrafish
38. Regulations, Policies and Guidelines Pertaining to the Use of Zebrafish in Biomedical Research
III. Diseases
39. Water Quality and Idiopathic Diseases of Laboratory Zebrafish
40. Important Parasites of Zebrafish in Research Facilities
41. Bacterial and Fungal Diseases of Zebrafish
42. Viral Diseases
43. Nonexperimentally Induced Neoplastic and Proliferative Lesions in Laboratory Zebrafish
44. Special Procedures for Zebrafish Diagnostics
45. Zebrafish as a Model to Understand Vertebrate Development
46. Zebrafish as a Model for Revealing the Neuronal Basis of Behavior
47. Zebrafish as a Model to Understand Human Genetic Diseases
48. Zebrafiish as a Model for Investigating
49. Targeted Editing of Zebrafish Genes to Understand Gene Function and Human Disease Pathology
50. Zebrafish as a Platform for Genetic Screening
51. Zebrafish as a Platform for Drug Screening
vivarium professionals maintaining zebrafish colonies, veterinarians responsible for their care and well-being, zoologists and ethologists studying the species, and investigators/researchers using them to gain critical insights into human physiology and disease.
Judith S. Eisen, Ph.D., earned her Doctorate at Brandeis University. She is a professor at the University of Oregon and a member of the Institute of Neuroscience at Oregon. The focus of Eisen’s research is to understand the mechanisms underlying development and function of the vertebrate nervous system. Eisen uses zebrafish in her research.
Susan C. Farmer, DVM, Ph.D., is the Senior Clinical Veterinarian and Co-Director of the Zebrafish Research Facility at the University of Alabama. Services offered by the facility are husbandry, larviculture, cryopreservation and research support. Dr. Farmer have her DVM degree from Mississippi State University and her Ph.D. in Pathology/Experimental Pathology from the University of Alabama at Birmingham.
Karen Guillemin, Ph.D., earned her Doctorate at Stanford University. She is a Professor at the University of Oregon and a member of the Institute of Molecular Biology at Oregon. Dr. Guillemin studies host-microbe interactions in development and disease, and uses zebrafish in her research.
Michael Kent, Ph.D., is a Professor of Microbiology at Oregon State University in the College of Veterinary Medicine. Kent’s lab focuses on two major research areas: diseases of zebrafish in research facilities and impacts of pathogens on wild salm
- Presents a complete view of the zebrafish, covering their biology, husbandry, diseases and research applications
- Includes the work of world-renowned authors
- Provides the first authoritative and comprehensive treatment of zebrafish in biomedical research as part of the ACLAM series
Date de parution : 11-2019
Ouvrage de 718 p.
21.4x27.6 cm
Thèmes de The Zebrafish in Biomedical Research :
Mots-clés :
zebrafish; model organism; developmental model system; genome; optically transparent
