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Retrovirus-Cell Interactions

Langue : Anglais

Coordonnateur : Parent Leslie

Couverture de l’ouvrage Retrovirus-Cell Interactions

Retrovirus-Cell Interactions provides an up-to-date review of the interactions between retroviruses and the cells they infect, offering a comprehensive understanding of how retroviruses hijack cellular factors to facilitate virus replication. Drugs targeting viral enzymes have been developed to treat HIV; the next challenge is to inhibit virus-cell interactions as next generation treatment strategies. Organized according to the retrovirus' replication cycle, this book does not focus exclusively on HIV, but rather includes important findings in other retroviral systems, including animal retroviruses, retrotransposons, and endogenous retroelements to allow broad comparisons on important commonalities and differences.

1. Retrovirus Receptor Interactions and Entry Lorraine M. Albritton 2. Cellular Factors That Regulate Retrovirus Uncoating and Reverse Transcription Stephen P. Goff 3. Nucleoporins in Retroviral Replication: What’s Nup Got to Do with It? Anne Monette and Andrew J. Mouland 4. Virus–Host Interactions in Retrovirus Integration Alan N. Engelman and Goedele N. Maertens 5. Transcriptional Control and Latency of Retroviruses Bryan C. Nikolai and Andrew P. Rice 6. Teetering on the Edge: The Critical Role of RNA Processing Control During HIV-1 Replication Ahalya Balachandran, Liang Ming and Alan Cochrane   7. Nuclear RNA Helicases Support Early and Late Events in Retroviral Replication Gatikrushna Singh, Xiao Heng and Kathleen Boris-Lawrie 8. Role of Host Factors in the Subcellular Trafficking of Gag Proteins and Genomic RNA Leading to Virion Assembly Eunice C. Chen and Leslie Parent 9. Tumor Suppressor Gene 101: A Virus’ Multifunctional Conduit to the ESCRT Trafficking Machinery Carol A. Carter 10. The Role of Lipids in Retroviral Replication Abdul A. Waheed and Eric O. Freed 11. Cellular Immune Responses to Retroviruses Susan R. Ross 12. Noncoding RNAs in Retrovirus Replication Alice A. Duchon and Karin Musier-Forsyth 13. Cellular Control of Endogenous Retroviruses and Retroelements Suzanne Sandmeyer 14. Strategies to Discover Novel Cellular Factors Involved in Retrovirus Replication Rebecca J. Kaddis Maldonado, Eunice C. Chen and Leslie Parent

Physician, Professor of Medicine, Co-Director of the MD/PhD Program, Co-Leader of the Penn State CTSI Pilot and Collaborative Translational and Clinical Studies

Penn State College of Medicine

  • Provides a valuable starting point for people who want to develop a detailed understanding of retroviral replication
  • Includes future-thinking strategies, such as next-generation treatment and anti-retroviral therapeutics
  • Features important commonalities and differences among retroviral systems

Date de parution :

Ouvrage de 528 p.

15x22.8 cm

Disponible chez l'éditeur (délai d'approvisionnement : 14 jours).

160,74 €

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Mots-clés :

Aim2-like receptor; Alix; Assembly; B′-PP2A; BET protein; Capsid; CDK9Coregulators; cGAS; Cholesterol; Core helicase domain; Cyclin T1HIV-1Latency; Cytoskeleton; DDX1DDX3DHX9DHX30MOV10RNA-binding proteins; DNA recombination; Early events of life cycle; Endogenous retroviruses; Entry mechanism; Entry; Envelope glycoprotein; ESCRT; Facilitation factors; FG-repeat Nups; Fusion trigger; Gag proteins; Gag; Gene therapy; Genomic RNA packaging; Gypsy-like elements; HIV vaccine; HIV/AIDS; HIV; HIV-1HIV-1 vRNA-ribonucleoprotein (RNP) complex export; HIV-1hnRNP; Host cell dependency factors; Innate immunity; Innate/intrinsic immunity; Integrase; Integration; Interferon; LEDGF/p75Retrovirus; Lipid rafts; Long interspersed elements; Long terminal repeat; Membrane fusion; MMTV; MVB; Nedd4PTAP; NoncodingRNA; Nuclear pore complex (NPC)Nucleocytoplasmic transport; Nucleoporin (Nup)Nup62Nup85Nup98Nup107Nup133Nup153Nup155Nup160Nup214 (CAN)Nup358 (RanBP2)Other viruses; Pattern recognition receptor; Phospholipids; piRNA; Placental development; Pom121Proviral integration; Proviral transcription; P-TEFb; Replication; Restriction factor; Restriction factors; Retrotransposons; Retrovirus assembly; Retrovirus entry; Retrovirus-cell interactions; Retrovirus; Retroviruses; Reverse transcription; RNA interference; RNA splicing; RNA trafficking; Sec13Tpr; Short interspersed elements; Six-helix bundle; Sphingolipids; SR protein; Therapeutics; Trafficking; Transcription; TRIM5ɑ tRNA; Ubiquitin; Uncoating; Upf1Viral preintegration complex (PIC) import; Viral replication; Viral sensors; Virus budding; Virus coevolution; Virus family- and genera-nucleoporin phylogeny; Virus receptor; Virus-host interaction

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