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Receptor Tyrosine Kinases, 1st ed. 2015 Family and Subfamilies

Langue : Anglais

Coordonnateurs : Wheeler Deric L., Yarden Yosef

Couverture de l’ouvrage Receptor Tyrosine Kinases
This book devotes a chapter to each RTK family and the multiple receptors within each family, thoroughly covering all of the RTKs. The chapters all follow the same structure, presenting this essential information in an accessible and user-friendly format. Each chapter covers one specific family of receptors and begins with a general introduction to that family and a comprehensive discussion of that receptor’s family in development and human disease. Following are in-depth analyses of each family’s receptors with discussions on the gene, protein, ligands, activation, and signaling pathways along with discussion of receptor processing and signal attenuation. Further, cross talk with other receptors systems, post-translational modification, and specific unique characteristics to each RTK are discussed. Because it isolates and explains each family, this book is an essential companion volume to Receptor Tyrosine Kinases: Structure, Functions and Role in Human Disease, by the same authors, which talks about RTKs more generally and without the family-by-family detail.

ALK Receptor Family.- TAM Receptor Family.- DDR Receptor Family.- EGFR Receptor Family.- EPHA Receptor Family.- FGFR Receptor Family.- INSR Receptor Family.- MET Receptor Family.- MUSK Receptor Family.- PDGFR Receptor Family.- PTK7 Receptor Family.- RET Receptor Family.- ROR Receptor Family.- Ros Receptor Family.- RYK Receptor Family.- TIE Receptor Family.- TRK Receptor Family.- VEGFR Receptor Family.- NOK Receptor Family.

Dr. Deric Wheeler received an M.S. in pathology from the University of Iowa and a Ph.D. in Cancer Biology from the University of Wisconsin. He conducted his postdoctoral training at the Fred Hutchinson Cancer Research Center in Seattle, WA, and at the University of Wisconsin School of Medicine and Public Health in Madison, where he eventually transitioned to faculty as an assistant professor in the department of human oncology. Dr. Wheeler’s lab research centers on resistance to molecular targeting agents and the role of subcellular localization of receptor tyrosine kinases and their roles in oncogenesis.

Dr. Yosef Yarden received a Ph.D. in Molecular Biology from the Weizmann Institute of Science in Rehovot, Israel. He completed postdoctoral training at Genentech, Inc. in San Francisco and at the Massachusetts Institute of Technology in Cambridge. He returned to the Weizmann Institute of Science first as an assistant professor and then later as a full professor. His past administrative responsibilities at the Weizmann Institute include Dean of the Faculty of Biology, Vice-President for Academic Affairs, Director of the M.D. Moross Institute for Cancer Research, and Dean of the Feinberg Graduate School. Dr. Yarden’s lab research centers on the roles played by growth factors and receptor tyrosine kinases in tumor progression.

Highlights each RTK family and the multiple receptors within each family

Discusses each receptor’s family in development and human disease

Analyses each family’s receptors, receptor processing and signal attenuation

Date de parution :

Ouvrage de 878 p.

15.5x23.5 cm

Disponible chez l'éditeur (délai d'approvisionnement : 15 jours).

Prix indicatif 197,18 €

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Date de parution :

Ouvrage de 878 p.

15.5x23.5 cm

Disponible chez l'éditeur (délai d'approvisionnement : 15 jours).

Prix indicatif 242,64 €

Ajouter au panier
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