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Principles of Molecular Medicine (2nd Ed., 2nd ed. 2006)

Langue : Anglais

Coordonnateurs : Runge Marschall S., Patterson Cam

Couverture de l’ouvrage Principles of Molecular Medicine
The concept of molecular medicine dates back to Linus means that there are many new opportunities and challenges Pauling, who in the late 1940s and early 1950s generalized for clinical medicine. One of the effects of the completion of from the ideas that came from the study of the sickle cell the Human Genome Project is the increasing application of hemoglobin molecule. With the first cloning of human genes the fields of molecular biology and genetics to the und- about 1976, molecular genetics took the molecular perspec- standing and management of common diseases. Assimi- tive on disease to the level of DNA. The term molecular tion of the new developments since the first edition has been medicine achieved wide currency in the 1980s with the ably accomplished by Drs. Runge and Patterson with the assignment of this designation to journals, at least one soci- help of their many knowledgeable authors. ety, institutes, and academic divisions of departments of in- As was evident in the first edition, molecular genetics is ternal medicine. Undoubtedly, molecular medicine has been involved in every specialty of medicine. A recurrent theme abetted by the Human Genome Project, which has aided in that edition, perhaps even more striking in the present one, greatly in the molecular characterization of disease.
I. Genetics Terry Magnuson and James P. Evans Mendelian Inheritance, Bruce R. Korf. Nontraditional Inheritance Shawn E. McCandless and Suzanne B. Cassidy Identifying Causal Genetic Factors Christopher I. Amos, John S. Witte, and William G. Newman Cancer Genetics and Molecular Oncology Sharon E. Plon Pharmacogenetics Renee E. Edkins and Dennis J. Cheek Hemophilia as a Model Disease for Gene Therapy of Genetic Disorders Jay Lozier Genetic Counseling Robin L. Bennett Animal Models in Biomedical Research: Ethics, Challenges, and Opportunities Robert W. Williams Ethical, Legal, and Social Implications Marcia Van Riper II. Cardiology Anthony Rosenzweig Congenital Heart Disease Lazaros K. Kochilas and Alvin J. Chin Inherited Cardiomyopathies Carolyn Y. Ho and Christine E. Seidman Heart Failure: Emerging Concepts in Excitation-Contraction Coupling and b-Adrenoceptor Coupling Clive J. Lewis, Federica del Monte, Sian E. Harding, and Roger J. Hajjar Aortic Diseases Saumya Das, James L. Januzzi, Jr., and Eric M. Isselbacher Atherosclerotic Coronary Disease Robert E. Gerszten and Anthony Rosenzweig Lipid Metabolism and Coronary Artery Disease Mason W. Freeman Hypertension Khurshed A. Katki and Donald J. DiPette Cardiac Hypertrophy Thomas Force and Jeffrey D. Molkentin Arrhythmias Barry London Genomics Calum A. MacRae and Christopher J. O'Donnell Cardiovascular Gene Therapy David A. Dichek III. Pulmonary Diseases Richard C. Boucher and Peadar G. Noone Idiopathic Interstitial Pneumonias Talmadge E. King, Jr. Asthma Stephen T. Holgate, Gordon Dent, and Mark G. Buckley Pulmonary Emphysema Steven D. Shapiro Pulmonary Hypertension Brian Fouty and David M. Rodman Acute Lung Injury David C. Christiani and Michelle Ng Gong Primary Ciliary Dyskinesia Peadar G. Noone, Maimoona Zariwala, and Michael R. Knowles Cystic Fibrosis Scott H. Donaldson and Richard C. Boucher Gene Therapy for Lung Diseases Jane C. Davies, Duncan M. Geddes, and Eric W.F.W. Alton Sarcoidosis Kelly D. Chason and Stephen L. Tilley Disorders of Pulmonary Surfactant Homeostasis Jeffrey A. Whitsett, Susan E. Wert, and Bruce C. Trapnell IV. Endocrinology Michael J. McPhaul Mechanisms of Hormone Action Stephen R. Hammes, Carol A. Lange, and Michael J. McPhaul Diabetes Mellitus William L. Lowe, Jr. Pituitary Function and Neoplasia Shlomo Melmed Growth Hormone Deficiency Disorders Amy Potter and John A. Phillips, III. Thyroid Disorders Peter Kopp Disorders of the Parathyroid Gland Andrew Arnold and Michael A. Levine Congenital Adrenal Hyperplasia Robert C. Wilson and Maria I. New Adrenal Diseases Richard J. Auchus, William E. Rainey, and Keith L. Parker Multiple Endocrine Neoplasia Type 1 Rajesh V. Thakker Multiple Endocrine Neoplasia Type 2 Robert F. Gagel, Sarah Shefelbine, Hironori Hayashi, and Gilbert Cote Disorders of Sex Determination and Differentiation Charmian A. Quigley Sex Chromosome Disorders Andrew R. Zinn Disorders of Pubertal Development Tomonobu Hasegawa Defects of Androgen Action Michael J. McPhaul Molecular Endocrinology of the Testis Marco Marcelli, Glenn R. Cunningham, José M. Garcia, Kirk C. Lo, and Dolores J. Lamb Ovarian Diseases Elizabeth A. McGee and Tammy L. Loucks V. Metabolic

Includes supplementary material: sn.pub/extras

Date de parution :

Ouvrage de 1268 p.

21x29.7 cm

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