Pharmaceutical Biotechnology : an Introduction for Pharmacists and Pharmaceutical Scientists (2nd updated Ed.) (paperback)

The field of pharmaceutical biotechnology is a rapidly evolving subject. A whole new arsenal of protein pharmaceuticals is being produced by recombinant techniques for a spectrum of serious diseases such as cancer, viral infections, cardiovascular and hereditary disorders. In addition, we are confronted with new technologies such as polymerase chain reactions, combinatorial chemistry and gene therapy. Completely revised and updated, this introductory textbook provides extensive coverage of both the basic science and the applications of biotechnology-produced pharmaceuticals, with special emphasis on their clinical use.

Molecular Biotechnology. Biophysical and Biochemical Analysis of Recombinant Proteins Structure and Analysis of Proteins. Production and Downstream Processing of Biotech Products. Formulation of Biotech Products, Including Biopharmaceutical Considerations. Pharmacokinetics and Pharmacodynamics of Peptide and Protein Drugs. Genomics, Proteomics and Additional Biotechnology-Related Techniques. Gene Therapy. Hematopoietic Growth Factors. Interferons and Interleukins. Insulin. Growth Hormones. Vaccines. Monoclonal Antibody-Based Pharmaceuticals. Appendix A: Trastuzumab/Herceptin. Appendix B: Abciximab/ReoPro. Appendix C: Daclizumab/Zenapax and Basiliximab/Simulect. Recombinant Thrombolytic Agents. Recombinant Coagulation Factors. Recombinant Human Deoxyribonuclease. Follicle-Stimulating Hormone. Dispensing Biotechnology Products: Handling, Professional Education and Product Information. Economic Considerations in Medical Biotechnology. Biotechnology Products in the Pipeline.