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Natural Products Chemistry Sources, Separations and Structures

Langue : Anglais

Auteur :

Couverture de l’ouvrage Natural Products Chemistry

Notoriously cumbersome to isolate and challenging to synthesize, the path of natural products to viable drugs is an arduous journey. Yet compounds isolated from nature have long been known to possess fascinating structures, biological profiles and pharmaceutical potential far greater than anything made by man. Natural Products Chemistry: Sources, Separations and Structures presents a practical guide to sourcing, isolating, and discovering new compounds from nature many of which become pharmaceutical drugs. This book emphasizes the challenges and advantages of products acquired from nature, compared to those obtained from combinatorial chemistry. A basic introduction, the book describes the whole cycle from farm to final compound, backed up by case studies drawn from industry and research applications. It broadens the scope of applications and draws upon examples from various sources. Natural products chemistry, as taught today, draws its examples mainly from marine chemistry or plant chemistry; however, there is also a fascinating and rich world of fermented (microbial and algal) products leading to complex structures. Thus, the book draws upon examples from the microbial world and from insects too. Therefore, this is a source of bioactive metabolites, not traditionally available in academic settings, more the mainstay of the pharmaceutical industry. Providing a roadmap of the process of collecting a compound from nature, isolating the active ingredient, and determining the chemical structure, this book provides a unique approach to the world of natural products.

History of Natural Products
Terrestrial
Marine
Bioprospecting

Biological and Pharmacological Aspects

Fractionation and Isolation

Structure Elucidation
X-ray crystallography
NMR
Mass Spectrometry

Biosynthesis

Chemical Synthesis
Optimization for Mass Production and Manufacturing

Medicinal Applications

Integrating with System Biology
Computational Chemistry

Sustainability
Biopiracy
Environmental Protection
International Treaties

Translation
Curation and Digitization
Intellectual Property
Licensing and Strategy

Undergraduate students in chemistry of natural products, advanced organic chemistry, and medicinal chemistry; graduate students in chemistry, medicinal plants, herbal science, and pharmaceutical science; and scientists and engineers in chemistry, engineering, pharmacy, pharmacognosy, and law.

Date de parution :

15.6x23.4 cm

Disponible chez l'éditeur (délai d'approvisionnement : 13 jours).

Prix indicatif 202,33 €

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Date de parution :

Ouvrage de 206 p.

15.6x23.5 cm

Disponible chez l'éditeur (délai d'approvisionnement : 13 jours).

Prix indicatif 90,46 €

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