Methods of Therapeutic Drug Monitoring Including Pharmacogenetics (2nd Ed.) Handbook of Analytical Separations Series
Coordonnateur : Hempel Georg
Methods of Therapeutic Drug Monitoring Including Pharmacogenetics, Second Edition, Volume Seven in the Handbook of Analytical Separations series, covers all aspects of drug monitoring, including laboratory work, pharmacokinetic analysis and clinical aspects, thus enabling readers from different fields to understand the whole process of therapeutic drug monitoring and how to avoid common pitfalls. The book contains analytical techniques for the quantification of drugs, along with pharmacogenetic and pharmacogenomic methods. Also included are updates on sample preparation, including dried blood spot technology and microextraction methods. In addition, the book includes new drugs, such as tyrosine kinase inhibitors and the monitoring of immunosuppressant drugs.
2. Chromatograpghic Methods for the Analysis of Drugs in Biological Fluids
3. Mass Spectrometry for the Quantification of Drugs in Biological Fluids
4. Capillary Electrophoresis for the Determination of Drugs in Biological Fluids
5. Immunoassays for the Determination of Drugs in Biological Fluids
6. Validation of Bioanalytical Methods for the Quantification od Drugs in Biological Fluids
7.Pharmocokinetic Methods for the Analysis, Interpretation, and Management of TDM Data for Individualising Drug Dosage Regimens Optimally
8. Therapeutic Drug Monitoring of Antibiotics in Critically Ill Patients
9. Therapeutic Drug Monitoring of Antifungals
10. Therapeutic Drug Monitoring of Antiepileptic Drugs
11. Therapeutic Drug Monitoring Antipsychotic and Antidepressant Drugs
12. Monitoring Immunosuppressant Drugs
13. Dose and Therapy Individualisation in Cancer Chemotherapy
14. Pharmacogenomics
Analysts working on drug analysis in clinical chemistry; analytical chemists of all levels of expertise that are outside the TDM field but desire to learn about it; hospital pharmacists involved in therapeutic drug monitoring; physicians and PharmDs that rely on these measurements to guide their decisions; other researchers in the field of drug monitoring
His research interests include bioanalytical methods for the quantification of drugs in biological fluids, especially capillary electrophoresis, pharmacometrics for therapy optimisation in special patient groups and medication management.
- Presents a unique, interdisciplinary approach that appeals to a wide range of users
- Written by authors from international labs, providing a global perspective that can be applied in various regulatory environments
- Features additional therapeutic drugs to reflect the rising number of immunocompromised patients
- Includes a new mass spectroscopic methods chapter to capture the frequent use in TDM and the improved availability of LC-MS across laboratories
Date de parution : 10-2019
Ouvrage de 380 p.
19x23.3 cm
Thème de Methods of Therapeutic Drug Monitoring Including... :
Mots-clés :
Accuracy; Antibiotics; Antibody; Antiepileptic drugs; Antiepileptics; Antifungal agents; Antigen; Assay error polynomial; Biological specimens; Capillary electrophoresis; Carryover; Central nervous system; Chromatography; Clearance; Cyclosporine A; Dried blood spots; Drugs of abuse; Drugs; Electronic medical record; Everolimus; Fisher information matrix; Gas chromatography; High performance liquid chromatography; High-performance liquid chromatography; High-throughput analysis; Immunoassay; Immunoglobulin; Immunosuppressive drug; Integrated circuit; Ligand-binding assay; Liquid chromatography; Liquid-liquid extraction; Liquid-phase microextraction; Mass spectrometry; Maximal tolerated dose; Metabolism; Micellar electrokinetic capillary chromatography; Miniaturization; Multiple model optimal design; Mycophenolic acid; Mycoses; Neutropenia; Nucleus accumbens; Pharmacodynamics; Pharmacokinetics; Pharmacology; Pharmakokinetics; Precision; Proton pump inhibitor; Sample preconcentration; Sample preparation; Serum; Sirolimus; Solid-phase extraction; Solid-phase microextraction