Iron Metabolism: Hepcidin Vitamins and Hormones Series

Iron Metabolism, Volume 110, the latest release in the Vitamins and Hormones series first published in 1943, covers the field of hormone action, vitamin action, X-ray crystal structure, physiology and enzyme mechanisms, with this release focusing on topics relating to hepcidin, bacterial infection, and iron overload, the role of heparan sulfates in hepcidin regulation, hepcidin CDNA and human gene sex hormones, growth factors and hepcidin, HFE gene polymorphisms and hereditary hemochromatosis, hepcidin and il-1beta, hepcidin-ferroportin axis, cardiomyocyte hepcidin, adipocyte iron, leptin and hepcidin, regulators of hepcidin expression, and much more.

1. Hepcidin, bacterial infection, and iron overloadRon Acton and James Barton2. The role of heparan sulfates in hepcidin regulationPaolo Arosio3. hepcidin CDNa and human geneMohamed Boumaiza4. Sex hormones, growth factors and hepcidinParesh Dandona5. HFE gene polymorphisms and hereditary hemochromatosisNikolaos Drakoulis6. HEPCIDIN & IL-1betaFunaba Masayuki7. Hepcidin-ferroportin axisYelene Ginzburg8. Cardiomyocyte hepcidinSamira Lakhal-Littleton9. Adipocyte iron, leptin and hepcidinDonald A. McClain10. Regulators of hepcidin expressionMarie-Paule Roth and Helene Coppin11. Splicing variant of hepcidin mRNAKatsunori Sasaki12. Hepcidin and the bmp-smad pathwayLaura Silvestri, Antonella Nai and Alessia Pagani13. Hfe/Tfr2 null mice and hepcidinNathan Subrumaniam

The scope will range from intense basic science to the molecular and physiological aspects of a particular disease state. The audience includes all basic scientists and clinicians interested in the focus of a given volume.

Dr. Litwack has authored 3 textbooks on biochemistry and hormones (one with John Wiley & Sons and 2 with Academic Press/Elsevier) and he has edited more than 70 volumes in the Vitamins & Hormones series (Academic Press/Elsevier); he has edited 14 volumes entitled Biochemical Actions of Hormones (Academica Press); He has edited (with David Kritchevsky) Actions of Hormones on Molecular Processes (Academic Press)

• Focuses on the newest aspects of hormone action in connection with diseases
• Lays the groundwork for the focus of new chemotherapeutic targets
• Represents reviews on emerging areas in hormone action, cellular regulators and signaling pathways