Investigative Immunotoxicology
Coordonnateurs : Tryphonas Helen, Fournier Michel, Blakley Barry R., Smits Judit, Brousseau Pauline
Investigative Immunotoxicology provides a critical evaluation of proposed experimental animal models and approaches, and discusses the contribution that immunotoxicity can make to the overall assessment of chemical-induced adverse health effects on humans and the ecosystem. Following a review of general concepts in immunotoxicology, the book discusses emerging methodologies at the cellular and molecular levels, and describes advances in and requirements for animal model development in testing the allergenicity of foods and genetically modified products. It presents animal models of autoimmunity associated with chemical exposure, includes recommendations for the selection of sentinel species in ecotoxicology, and presents an in-depth review of immunotoxicology as it relates to a variety of wildlife species. Finally, the book explains the role of immunotoxicology in human health risk assessment and the regulatory process.
Outlining the potential chemical hazards facing human and ecosystem health, this is a valuable reference for professionals and researchers in immunotoxicology and risk assessment. It also deserves the attention of the pharmaceutical industry and environmental toxicologists who are concerned about the effects of xenobiotics on ecosystems.
Date de parution : 09-2019
17.8x25.4 cm
Date de parution : 01-2005
Ouvrage de 480 p.
17.8x25.4 cm
Thèmes d’Investigative Immunotoxicology :
Mots-clés :
CRC Press LLC; Immunotoxic Effects; Chemical Exposure; Host Resistance Assays; LLNA; BN Rat; Immune Alteration; IgE Response; Immune Markers; Developmental Immunotoxicology; IgE Antibody Response; Marine Mammals; Harbor Seal; PFC; Mesenteric Lymph Node; Mucosal Immunity; Van Loveren; De Guise; Immunotoxicology Studies; Food Allergy; IgE Antibody; Guinea Pig Model; Oxidative Burst Assay; Food Allergens; Allergen Specific IgE Production