Introduction to Biotechnology, Global Edition (4^th Ed.)

For courses in biotechnology.

Introduction to Biotechnology brings the latest information students need to understand the science and business of biotechnology. The popular text emphasizes the future of biotechnology and the biotechnology student?s role in that future with balanced coverage of basic cell and molecular biology, fundamental techniques, historical accounts, new advances, and hands-on applications.

The 4th Edition features content updates in every chapter that reflect the most relevant, up-to-date changes in technology, applications, ethical issues, and regulations. Additionally, every chapter now includes an analytic Case Study that highlights current research and asks students to use what they?ve learned about key chapter concepts to answer questions. New Career Profiles, written by biotech professionals and available on the Companion Website along with additional career resources, highlight potential jobs in the biotech industry. The chapter on biotechnology regulations has been revised to include regulations involving international bodies.

• 1. The Biotechnology Century and Its Workforce
• 2. An Introduction to Genes and Genomes
• 3. Recombinant DNA Technology and Genomics
• 4. Proteins as Products
• 5. Microbial Biotechnology
• 6. Plant Biotechnology
• 7. Animal Biotechnology
• 8. DNA Fingerprinting and Forensic Analysis
• 9. Bioremediation
• 10. Aquatic Biotechnology
• 11. Medical Biotechnology
• 12. International Biotechnology Regulations
• 13. Ethics and Biotechnology
• Appendix I: Answers to Questions
• Appendix II: The 20 Amino Acids of Proteins
• Glossary
• Index

William J. Thieman taught biology at Ventura College for 40 years and biotechnology for 11 years before retiring from full time teaching in 2005. He continues to serve as an advisor to the college biotechnology program. He received his B.A. in biology from California State University at Northridge in 1966 and his M.A. degree in Zoology in 1969 at UCLA. In 1995, he started the biotechnology program at Ventura College. In 1998, he added the laboratory skills course, and it was articulated as a state-approved vocational program. He identified technical skills needed for the program while serving three summer internships at Amgen, Biosource (now Invotrogen) and Biopool. The internships provided an opportunity to learn protocols, interact with lab directors, and query technicians, focusing on identifying the skills needed in these biotechnology companies. He routinely engaged his contacts at these biotechnology companies to lead lab protocols and describe their experiences to his classes.

Mr. Thieman has taught a broad range of undergraduate courses including general, human, and cancer biology. He received the Outstanding Teaching Award from the National Association of Biology Teachers in 1996 and the 1997 and 2000 Student Success Award from the California Community Colleges Chancellor’s Office. The Economic Development Association presented its 1998 Program for Economic Development Award to the biotechnology training program at Ventura College for its work with local biotechnology companies. His success in acquiring grants to support the program was recognized at the 2007 Conference of the National Center for Resource Development.

Michael A. Palladino is Vice Provost for Graduate Studies, former Dean of the School of Science and Professor of Biology at Monmouth University in West Long Branch, New Jersey. He received his B.S. degree in Biology from Trenton State College (now known as The College of New Jersey) in 1987 and

• A “Business of Biotechnology” section in Chapter 1 describes biotech company organisation and structure, top biotechnology and pharmaceutical companies, and features updated data on the biotechnology industry worldwide.
• Concise overviews examine cutting-edge techniques and concepts including bioinformatics, proteomics, gene editing, and genomics, as well as detailed information on agricultural, medical, forensic, and regulatory issues that impact the biotechnology industry.
• Coverage of recent research and developments includes discussions of gene editing approaches like CRISPR, precision medicine, immunotherapies, biosimilar drugs, transgenic crops, 3D bioprinting of tissues and organs, the Human Microbiome Project, and the Cancer Atlas Genome Project.
• Tools of the Trade Boxes provide details on modern techniques and methods related to each chapter’s content and the biotech industry.
• Making a Difference inspires and engages students by discussing how real people, real companies, and real organisations are putting biotech to use to improve the quality of life. Making a Difference appears at the end of each chapter and provides short case studies that contain an example of the chapter’s content and how it can be applied in the real world.
• A revised Chapter 12 discusses international regulatory authorities that oversee biotechnology regulations.
• Forecasting the Future begins each chapter and highlights biotechnology-driven questions that have yet to be answered, are in the process of being researched, or are topics/research/policy that are under development and will have an impact on our future. This feature demonstrates to students that biotechnology is a dynamic field, encompassing a broad range of career options, and that there are still many problems and questions that they can get involved in solving and answering.