Hydrogenosomes and Mitosomes: Mitochondria of Anaerobic Eukaryotes (2^nd Ed., 2nd ed. 2019) Microbiology Monographs Series, Vol. 9

"Hydrogenosomes and Mitosomes: Mitochondria of Anaerobic Eukaryotes" provides a summary of the current knowledge of these organelles which occur in unicellular, often parasitic organisms, including human pathogens. These organelles exhibit a variety of structures and functions. This work describes properties such as protein import, structure, metabolism, adaptation, proteome and their role in drug activation and resistance. Further topics include organelle evolution and biogenesis.

Introduction, history etc.., Miklos Müller, The Rockefeller University, USA,- Anaerobic Eukaryotes in Persuit Normality: the Eolution of mitochondria-derived organelle, William Martin, Germany,- Protein Import into Hydrogenosomes and Mitosomes, Abhijith Radhakrishna Makki, Jan Tachezy, Pavel Doležal,- Structure of the Hydrogenosome (morphogenesis, electron microscopy, comparison of various hydrogenosomes..), Marlene Benchimol, Brasil,- Hydrogenosomes of anaerobic ciliates, Johannes H.P. Hackstein, The Netherlands,- Metabolism of trichomonad hydrogenosomes (energy metabolism, electron transport…), Ivan Hrdy, Charles University, Czech Republic,- Hydrogenosomes of anaerobic chytrids (Neocallimastix, Piromyces), L. Tielens,  J. Hellemond, F. Voncken, J. Heckstein,- The proteome of T. vaginalis hydrogenosomes, Petr Rada Charles University, Czech Republic,- Mitosomes in parasitic protists: Entamoeba histolytica, Giardia intestinalis, microsporidia…, J. Tachezy, Pavel Doležal,- Remnant mitochondria of Cryptosporidium parvum, Anastasios Tsaousis, UK,- Mitochondrion-derived organelles in free-living protists, A. Roger M. Kolísko,-  Organisms without mitochondria, how it may happen?, V. Hampl.

Compares the biogenesis, structure, and function of various type of mitochondria in distinct eukaryotic lineages

Provides new a new perspective on mitochondria origin and the evolution of eukaryotic cells

Investigates the constraints that led to the reduction of mitochondria in parasitic protists , furthering our understanding of the evolution of parasitism