Enantioselection in Asymmetric Catalysis
Auteurs : Gridnev Ilya D., Dub Pavel A.
The field of asymmetric catalysis is currently one of the hottest areas in chemistry. This unique book focuses on the mechanism of enantioselectivity in asymmetric catalysis, rather than asymmetric catalysis from the synthetic view. It describes reliable, experimentally and computationally supported mechanisms, and discusses the danger of so-called "plausible" or "accepted" mechanisms leading to wrong conclusions. It draws parallels to enzymatic catalysis in biochemistry, and examines in detail the physico-chemical aspects of enantioselective catalysis.
Introduction. General Physico-Chemical Description of the Enantioselective Catalysis. Asymmetric Catalysis by Chiral Complexes of Transition Metals. Asymmetric Organocatalysis. Asymmetric Autocatalysis and Amplification of Chirality. Conclusion.
Ilya Gridnev is an associate professor at Tohoku University, Sendai, Japan. Pavel A. Dub is a J. Robert Oppenheimer postdoctoral fellow at Los Alamos National Laboratory, New Mexico, USA.
Date de parution : 12-2016
15.6x23.4 cm
Date de parution : 12-2019
15.6x23.4 cm
Thèmes d’Enantioselection in Asymmetric Catalysis :
Mots-clés :
American Chemical Society; Catalytic Cycle; enantioselective; Dimethyl Malonate; chiral; Chiral Phosphoric Acid; asymmetric catalysis; Pyrimidinyl Rings; asymmetric induction; NMR Investigation; chiral catalysts; Diastereomeric Transition States; Cinchona Alkaloids; Enantioselection; Organoboronic Acids; Biochemistry; Arylboronic Acids; Organocatalytic reactions; Reaction Pool; Enantioselective catalysis; Orange Dotted Lines; AH; Chelate Cycle; Migratory Insertion; Catalytic Asymmetric Reaction; NMR Spectrum; NMR Experiment; Low Temperature Hydrogenation; Oxidative Addition; Friedel Crafts Alkylation; Rh Complexes; Dalton Trans; Hydrogenation Product; Double Bond