Carbonic Anhydrase: Mechanism, Regulation, Links to Disease, and Industrial Applications, 2014 Mechanism, Regulation, Links to Disease, and Industrial Applications Subcellular Biochemistry Series, Vol. 75
Coordonnateurs : Frost Susan C., McKenna Robert
Preface. Part I Introduction.- Overview of the Carbonic Anhydrase Field.- Part II Carbonic Anhydrases: Ancient but Relevant. Physiological Functions of the Alpha Class of Carbonic Anhydrases.- Catalytic Mechanism of α-Class Carbonic Anhydrases: CO2 Hydration and Proton Transfer.- Structure and Catalytic Mechanism of b-Carbonic Anhydrases.- Prokaryotic Carbonic Anhydrases of Earth’s Environment.- Carboxysomal Carbonic Anhydrases.- Carbonic Anhydrases and their Interplay with Acid/base-coupled Membrane Transporters.- Carbonic Anhydrase Related Proteins: Molecular Biology and Evolution.- Membrane Associated Carbonic Anhydrase IV (CA IV): A Personal and Historical Perspective.- Carbonic Anhydrase Expression in Kidney and Renal Cancer: Implications for Diagnosis and Treatment.- Carbonic Anhydrase IX: Regulation and Role in Cancer.- Carbonic Anhydrase IX as an Imaging and Therapeutic Target for Tumors and Metastases.- Carbonic Anhydrase IX (CAIX) as a Mediator of Hypoxia-induced Stress Response in Cancer Cells.- Carbonic Anhydrases and Brain pH in the Control of Neruronal Excitability.- Carbonic Anhydrase Inhibitors: Drug Design.- Natural Products that Inhibit Carbonic Anhydrases.- Glaucoma and the Application of Carbonic Anhydrase Inhibitors.- Carbonic Anhydrase Inhibitors and High Altitude Illnesses.- Thermal-Stable Carbonic Anhydrases: A Structural Overview.- Carbonic Anhydrases in Industrial Applications. Index.
Date de parution : 08-2016
Ouvrage de 430 p.
15.5x23.5 cm
Date de parution : 11-2013
Ouvrage de 430 p.
15.5x23.5 cm
Thèmes de Carbonic Anhydrase: Mechanism, Regulation, Links to... :
Mots-clés :
carbonic anhydrase; industrial applications; mechanism; pathology; structure