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Biological Effects of Metal Nanoparticles, 1st ed. 2016

Langue : Anglais

Auteurs :

Couverture de l’ouvrage Biological Effects of Metal Nanoparticles

This book offers a comprehensive overview of recent studies conducted on the biological effects of metal nanoparticles. It also provides a solid theoretical foundation and various metal nanoparticle synthesis methods.

Part I reviews the main chemical methods used for synthesizing metal nanoparticles in a solution and describes original method of biochemical synthesis, as well as some special procedures developed specifically for studying the biological activity of nanoparticles.

Part II analyzes current literature on the effects of metal nanoparticles observed in microorganisms and addresses the influence of silver nanoparticles obtained by biochemical synthesis on biological objects on various organization levels, namely on microorganisms,  acellular slim mold, unicellular alga, plant seeds  and mammalian cells.

The last section explains the central problems common in studies on the biological effects of metal nanoparticles and outlines potential uses of this trend in bio-nanotechnologies.

This book is aimed at specialists, professors and students aspiring to expand their knowledge about the biological activities of metal nanoparticles and nanoparticle-containing materials.

CONTENTS
Abbreviations and designations
Introduction

Part I
PREPARATION AND CHARACTERIZATION  OF  METAL NANOPARTICLES IN SOLUTIONS

Chapter 1
Methods of the nanoparticles preparation in solutions LI. Introductory remarks
1.2. Principles used for the choice of methods
1.3. Chemical synthesis with traditional reducing agents
1.3.1.General considerations
1.3.2.Synthesis in water solution
1.3.3.Synthesis in the two-phase system and non-aqueous solutions
1.3.4.Synthesis in reverse micelles
1.4. Photo-and radiation-chemical synthesis
1.5. Electrochemical synthesis
1.6. Biological reduction in water solution
1.7. Summary

Chapter 2
Biochemical synthesis of metal nanoparticles
2.1. Prerequisites of the method
2.1.1.General information on the properties of flavonoids
2.1.2.AOT/isooctane reverse micelles
2.2. Cieneral scheme of the synthesis
2.3. Peculiarities of the experimental procedure
2.3.1.Preparation of the flavonoid micellar solution
2.3.2.Extinction coefficient determination for the flavonoids in micellar solution
2.4. Examples of the nanoparticles synthesis
2.4.1. Silver nanoparticles
2.4.2. Gold nanoparticles
2.4.3. Copper nanoparticles

Chapter 3
Development of
the biochemical synthesis for practical applications
Determination of the extinction coefficient for Ag nanoparticles
3.1.1. Extinction coefficient of the complex
3.1.2. Extinction coefficient of the nanoparticles
3.2. The effect of C Qr /C Ag  relation on the formation rate and yield of silver nanoparticles
3.3. Preparation of small nanoparticles with narrow size distribution
Chapter 4
Preparation of metal nanoparticles in water solutions on the basis of biochemical  synthesis
4.1. Preparation of nanoparticles as water dispersions by their transfer from micellar solution
4.2. Characteristics of silver and gold nanoparticles in water solution
4.2.1.Silver nanoparticles
4.2.2.Gold nanoparticles
4.3. Synthesis of silver and copper nanoparticles in water solution with natural stabilizers
4.3.1.Starch-stabilized Ag nanoparticles
4.3.2.Cyclodextrin-stabilized Ag nanoparticles
4.3.3.Starch-stabilized Cu nanoparticles
4.3.4.Comparison with the data found in literature

Chapter 5
Materials modified with metal nanoparticles
5.1. Creation of liquid-phase materials with metal nanoparticles
5.2. Solid materials with Ag and Cu nanoparticles


Part II
BIOLOGICAL EFFECTS OF MET
AL NANOPARTICLES
General information

Chapter 6
The effect of metal nanoparticles on biological objects (analysis
of the literature)
6.1. Metal nanoparticles effects observed on microorganisms
6.1.1. Antimicrobial activities of Ag nanoparticles<
6.1.2. Antimicrobial activities of Cu, Au and metal oxides nanoparticles....
6.2. On the mechanism of antimicrobial activities of metal nanoparticles
6.3. Summary

Chapter 7
Antimicrobial activity of nanoparticles stabilized by synthetic surface active substance7.1. Ag and Cu nanoparticles in liquid medium
7.1.1.Varnish-paint materials with biocidal properties
7.1.2.Water solutions of Ag nanoparticles
7.2. Solid materials and polymer films with Ag nanoparticles

Chapter 8
The effect of silver nanoparticles on some objects from the fungal and vegetable kingdoms
8.1. Plasmodium of the acellular slime mold Physarum polycephalum
8.2. Unicellular alga Chlorella vulgaris
8.3. Plant seeds

Chapter 9
The effect of silver nanoparticles on human cells in vitro and mammalians in vivo
9.1. The effect of Ag nanoparticles on cells in vitro
9.1.1.Toxicity of Ag nanoparticles for tumor cells. Stabilizationby AOT
9.1.2.Toxicity of Ag nanoparticles for normal cells. Stabilizationby starch
9.2. The effect of Ag nanoparticles on mammalian organism
9.3. Inferences from the results of our studies

Conclusion
References

Offers an up-to-date

overview of metal nanoparticles’ biological activities

Provides a theoretical

foundation and various metal nanoparticle synthesis methods

Outlines possible problems of studies on the biological effects of metal nanoparticles

Highlights various uses of metal nanoparticles in bio-nanotechnologies

Includes supplementary material: sn.pub/extras

Date de parution :

Ouvrage de 292 p.

15.5x23.5 cm

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