Bayesian Phylogenetics Methods, Algorithms, and Applications Chapman & Hall/CRC Computational Biology Series

Offering a rich diversity of models, Bayesian phylogenetics allows evolutionary biologists, systematists, ecologists, and epidemiologists to obtain answers to very detailed phylogenetic questions. Suitable for graduate-level researchers in statistics and biology, Bayesian Phylogenetics: Methods, Algorithms, and Applications presents a snapshot of current trends in Bayesian phylogenetic research.

Encouraging interdisciplinary research, this book introduces state-of-the-art phylogenetics to the Bayesian statistical community and, likewise, presents state-of-the-art Bayesian statistics to the phylogenetics community. The book emphasizes model selection, reflecting recent interest in accurately estimating marginal likelihoods. It also discusses new approaches to improve mixing in Bayesian phylogenetic analyses in which the tree topology varies. In addition, the book covers divergence time estimation, biologically realistic models, and the burgeoning interface between phylogenetics and population genetics.

Bayesian phylogenetics: methods, computational algorithms, and applications. Priors in Bayesian phylogenetics. IDR for marginal likelihood in Bayesian phylogenetics. Bayesian model selection in phylogenetics and genealogy-based population genetics. Variable tree topology stepping-stone marginal likelihood estimation. Consistency of marginal likelihood estimation when topology varies. Bayesian phylogeny analysis. Sequential Monte Carlo (SMC) for Bayesian phylogenetics. Population model comparison using multi-locus datasets. Bayesian methods in the presence of recombination. Bayesian nonparametric phylodynamics. Sampling and summary statistics of endpoint-conditioned paths in DNA sequence evolution. Bayesian inference of species divergence times. Index.

Ming-Hui Chen is a professor of statistics and director of the Statistical Consulting Services at the University of Connecticut. He was the recipient of the 2013 American Association of the University Professors Research Excellence Award, the 2013 College of Liberal Arts and Sciences Excellence in Research Award in the Physical Sciences Division at the University of Connecticut, and the 2011 International Chinese Statisticians Association (ICSA) Outstanding Service Award. An elected fellow of the ASA and the IMS, Dr. Chen has served on numerous professional committees, including the 2013 president of the ICSA, the 2011-2013 board of directors of the International Society for Bayesian Analysis, the 2007-2010 executive director of the ICSA, and the 2004-2006 board of directors of the ICSA. He has also served on editorial boards of Bayesian Analysis, Journal of the American Statistical Association, Journal of Computational and Graphical Statistics, Lifetime Data Analysis, Sankhya, and Statistics and Its Interface. His research interests include Bayesian statistical methodology, Bayesian computation, Bayesian phylogenetics, categorical data analysis, design of Bayesian clinical trials, DNA microarray data analysis, meta-analysis, missing data analysis, Monte Carlo methodology, prior elicitation, statistical methodology and analysis for prostate cancer data, and survival data analysis.

Lynn Kuo is a professor of statistics at the University of Connecticut. An elected fellow of the ASA, she was previously a research fellow in the Statistical Survey Institute at the USDA and at the Statistical and Applied Mathematical Sciences Institute (SAMSI). Dr. Kuo received an outstanding service award from ICSA in 2013 and was the secretary and treasurer of the Section of Bayesian Statistics of the ASA in 1998-1999. She has been an associate editor of the Journal of American Statistical Associati