Nanobiomaterials Handbook

Nanobiomaterials exhibit distinctive characteristics, including mechanical, electrical, and optical properties, which make them suitable for a variety of biological applications. Because of their versatility, they are poised to play a central role in nanobiotechnology and make significant contributions to biomedical research and healthcare. Nanobiomaterials Handbook offers a broad introduction for those new to the subject and serves as a useful reference for advanced professionals.

Analyzing major topics and disciplines in this arena, this volume:

• Defines scope, current status, and future prospects of nanobiomaterials
• Surveys nanobiomaterials and examines various synthesis and processing techniques important for developing nanobiomaterials
• Explores the unique nanoscopic physicochemical properties of nanobiomaterials
• Discusses potential applications, emphasizing unique challenges in the design, fabrication, and evaluation of biomaterials for a particular application or field
• Provides a detailed overview of the interactions between bionanomaterials/biological systems and the biocompatibility issues associated with bionanomaterials

Advances in nanobiomaterials requires a multidisciplinary approach spanning major fields in physical and biological sciences, engineering, and medicine with considerable collaboration between ethicists, regulatory bodies, and industry. This volume brings together the work of a team of world-renowned experts from various fields who discuss the vast potential for nanobiomaterials in a myriad of applications.

Nanobiomaterials: Current and Future Prospects. Multifunctional Gold Nanoparticles for Cancer Therapy. Synthesis, Processing, and Characterization of Ceramic Nanobiomaterials for Biomedical Applications. Synthesis, Properties, Characterization, and Processing of Polymeric Nanobiomaterials for Biomedical Applications. Carbon-Based Nanomedicine. Synthetic and Toxicological Characteristics of Silica Nanomaterials for Imaging and Drug Delivery Applications. Peptide-Based Self-Assembled Nanofibers for Biomedical Applications.Electrostatically Self-Assembled Nanomaterials. Peptide-Based Nanomaterials for siRNA Delivery: Design, Evaluation, and Challenges. Nucleic Acid Nanobiomaterials. Emerging Technologies in Nanomedicine. Nanomaterials for Therapeutic Drug Delivery. Nanobiomaterials for Nonviral Gene Delivery. Nanobiomaterials for Cancer-Targeting Therapy. Nanobiomaterials for Ocular Applications. Nucleic Acid Based Nanobiosensing. Nanobiomaterials for Molecular Imaging.Gadolinium-Based Bionanomaterials for Magnetic Resonance Imaging. Nanostructured Materials for Improved Magnetic Resonance Imaging. Nanobiomaterials for Dual-Mode Molecular Imaging: Advances in Probes for MR/Optical Imaging Applications. Nanoscale Probes for the Imaging of RNA in Living Cells. Nanomaterials for Artificial Cells. Nanobiomaterials for Musculoskeletal Tissue Engineering. Nanocomposite Polymer Biomaterials for Tissue Repair of Bone and Cartilage: A Material Science Perspective. Collagen: A Natural Nanobiomaterial for High-Resolution Studies in Tissue Engineering. Nanotopography on Implant Biomaterials. Nanoarray Bionanotechnology. Photopatternable Multifunctional Nanobiomaterials. Nanobiomaterials for Preclinical Studies and Clinical Diagnostic. Biocompatibility of Nanomaterials: Physical and Chemical Properties of Nanomaterials Relevant to Toxicological Studies, In Vitro and In Vivo. Hemocompatibility of Nanoparticles. Breaking the Carbon Barrier: Nanobiomaterials and Communal Ethics. Index.

Balaji Sitharaman is an assistant professor of biomedical engineering at Stony Brook University in New York. He received his BS (2000) from the Indian Institute of Technology, Kharagpur, and his MA and PhD (2005) from Rice University, Houston, Texas, where he also completed his postdoctoral research (2005–2007) as the J. Evan Attwell-Welch Postdoctoral Fellow at the Richard E. Smalley Institute for Nanoscale Science and Technology. Sitharaman’s research program is at the interface of nanotechnology, regenerative, and molecular medicine, and synergizes the advancements in each of these fields to tackle problems related to diagnosis/treatment of disease and tissue regeneration. He has authored over 50 publications and has eight patents. He has received several awards for his research, including NIH Director’s New Innovator Award from the National Institute of Health, the Idea Award from the Department of Defense, the Carol M. Baldwin Breast Cancer Research Award from the Carol Baldwin Foundation, and the George Kozmetsky Award from the Nanotechnology Foundation of Texas.