Features, Transmission, Detection, and Case Studies in COVID-19
Coordonnateurs : Rajendram Rajkumar, Preedy Victor R, Patel Vinood
Section A: SARS-CoV-2 and COVID-19: Introductory chapters and setting the scene
1. Coronavirus disease 2019 (COVID-19) pandemic in context: Systemic effects
2. Early warning of SARS-CoV-2 infection
3. Mobile phones and their use to study dynamics of the COVID-19 pandemic
Section B: Structure, transmission and avoidance
4. Cis regulatory elements: A novel communication route between the host cell and the SARS-CoV-2 genome
5. SARS-CoV-2 ORF8: Structure, evolution, molecular function, and its contribution to the
pathogenicity of the virus
6. SARS-CoV-2 spike protein binding ligands and its application in COVID-19 therapeutics
7. SARS-CoV-2 bulldozes the autophagy pathway and unhinges mitochondrial quality control
thereby driving neurodegeneration—A hypothesis
8. The Omicron variant of SARS-CoV-2
9. Monitoring SARS-CoV-2 spread in hospitals
10. Computational analysis of mutations in SARS-CoV-2 variants spike protein and protein
interactions
11. Airborne transmission of SARS-CoV-2
12. Reducing transmission of SARS-CoV-2 with face masks: Its potential protective effects
13. Digital twin of ventilation system against COVID-19 transmission and infection risk
14. Pets and SARS-CoV-2: What is their role in the epidemiology of the disease?
15. SARS-CoV-2 transmission in dental practice
16. SARS-CoV-2 compared with influenza and respiratory syncytial virus in terms of vertical
transmission
17. Reducing droplets and aerosols in the surgical setting and applications to the COVID-19
pandemic
18. SARS-CoV motion dynamics: Linking in droplet size
19. Ventilation and airborne particles in classrooms: Implications for the COVID-19 pandemic
20. Indoor transmission of the SARS-CoV-2 virus through aerosols emitted by e-cigarettes
Section C: Impact and effects
21. The Impact of COVID-19 on first responders
22. COVID-19 and suspected drug-induced liver injury
23. Pulmonary fibrosis in COVID-19
24. The effect of SARS-CoV-2 infection on cancer: Clinical correlation and
potential pathological mechanism
25. Severe SARS-CoV-2, plateletendothelium interactions, and cardiovascular injury
26. Cardiometabolic syndrome and COVID-19: Pathophysiological aspects
27. COVID-19 and type 1 and 2 diabetes: An overview
28. COVID-19 and older adults: An overview
29. COVID-19 and male fertility
30. COVID-19 and obesity: An overview
Section D: Treatments, strategies, and vaccines
31. COVD-19 vaccines and their impact: An overview
32. Exploring the promise of COVID-19 vaccines: A review of preclinical studies
33. Drugs actively being investigated for use in COVID-19
34. The biology of neutralizing antibody therapy with REGEN-COV
35. The intensive care unit and percutaneous tracheostomy in patients with coronavirus disease
2019
36. Cardiac effects of drugs and vaccines used to treat and prevent COVID-19
37. COVID-19 pandemic and isolation: Impact on sleep
38. Strategies in the COVID-19 pandemic: Disinfection of gloved hands
39. In silico studies on established antivirals on SARS-CoV-2 RNAdependent RNA polymerase
40. The COVID-19 cytokine storm and its immunomodulatory treatment
41. Safety and efficacy of nebulization for reducing the intensity of viral load and clinical manifestations in patients with COVID-19
Section E: Detection and biomarkers
42. Bronchoalveolar lavage (BAL) and use in detection of SARS-CoV-2
43. SARS-CoV-2 testing and vaccination among people who use drugs
44. Homocysteine as a biomarker in COVID-19
45. Assessment of smell and taste in COVID-19
46. S-gene analysis: RT-PCR and Sanger sequencing applied to SARS-CoV-2 virus
47. False-negative results in screening for SARS-CoV-2
48. Sample pooling and SARS-CoV-2 assays
49. Biomarkers of invasive mechanical ventilation in obesity and metabolic syndrome in patients
with COVID-19
Section F: Case studies with mini review
50. Hypoxia and heart-lung interactions in COVID-19: The significance of right heart dysfunction and shunt
51. Ulnar nerve dysfunction as COVID-19 sequelae
52. Case study: Coronavirus disease 2019 and acute kidney injury
53. Case study: The detection and treatment of a pneumothorax in a patient with coronavirus disease 2019 pneumonia
54. Proposal and demonstration of a survey method for the prevention of airborne transmission: Case studies in healthcare and welfare facilities
Section G: Resources
55. Recommended resources for the features, transmission, and detection of coronavirus disease
2019 (COVID-19)
Dr Rajkumar Rajendram is a clinician scientist with a focus on internal medicine, anaesthesia, intensive care and peri-operative medicine. He graduated with distinctions from Guy’s, King’s and St. Thomas Medical School, King’s College London in 2001. As an undergraduate he was awarded several prizes, merits and distinctions in pre-clinical and clinical subjects.
Dr Rajendram began his post-graduate medical training in general medicine and intensive care in Oxford. He attained membership of the Royal College of Physicians (MRCP) in 2004 and completed specialist training in acute and general medicine in Oxford in 2010. Dr Rajendram subsequently practiced as a Consultant in Acute General Medicine at the John Radcliffe Hospital, Oxford.
Dr Rajendram also trained in anaesthesia and intensive care in London and was awarded a fellowship of the Royal College of Anaesthetists (FRCA) in 2009. He completed advanced training in regional anaesthesia and intensive care. He was awarded a fellowship of the Faculty of Intensive Care Medicine (FFICM) in 2013 and obtained the European diploma of intensive care medicine (EDIC) in 2014. He then moved to the Royal Free London Hospitals as a Consultant in Intensive Care, Anaesthesia and Peri-operative Medicine. He has been a fellow of the Royal College of Physicians of Edinburgh (FRCP Edin) and the Royal College of Physicians of London (FRCP Lond) since 2017 and 2019 respectively. He is currently a Consultant in Internal Medicine at King Abdulaziz Medical City, National Guard Heath Affairs, Riyadh, Saudi Arabia.
Dr Rajendram’s focus on improving outcomes from Coronavirus Disease 2019 (COVID-19) has involved research on point of care ultrasound and phenotypes of COVID-19. Dr Rajendram also recognises that nutritional support is a fundamental aspect of medical care. This is particularly important for patients with COVID-19. As a clinician scientist he has therefore devoted significant time and effort into nutritional
- Discusses COVID-19 biology, including pathogenesis and transmission
- Describes systemic issues caused by COVID-19, including cardiovascular effects and loss of taste and smell
- Outlines detection methods, biomarkers associated with severity, and disease outcomes
- Features individual chapter introductions, summaries, and case studies to provide comprehensive descriptions of COVID-19 symptoms and effects
- Contains chapters with key facts, dictionary of terms, summary points, applications to other areas pertinent to each chapter, and policies and procedures
Date de parution : 06-2024
Ouvrage de 694 p.
21.5x27.6 cm
À paraître
Thèmes de Features, Transmission, Detection, and Case Studies in... :
Mots-clés :
COVID-19; coronavirus; stroke; brain hypoxia; virus transmission; Parkinson’s; olfactory system; vaccines; biomarkers
